Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 470111..470295 Replicon chromosome
Accession NZ_CP071594
Organism Staphylococcus aureus strain PNID0137

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag J3R87_RS02530 Protein ID WP_000482647.1
Coordinates 470188..470295 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 470111..470171 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J3R87_RS02515 465621..465788 - 168 Protein_492 hypothetical protein -
J3R87_RS02520 466019..467752 - 1734 WP_000486505.1 ABC transporter ATP-binding protein -
J3R87_RS02525 467777..469540 - 1764 WP_001064829.1 ABC transporter ATP-binding protein -
- 470111..470171 + 61 - - Antitoxin
J3R87_RS02530 470188..470295 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
J3R87_RS02535 470429..470815 - 387 WP_000779351.1 flippase GtxA -
J3R87_RS02540 471083..472225 + 1143 WP_001176855.1 glycerate kinase -
J3R87_RS02545 472285..472944 + 660 WP_000831298.1 membrane protein -
J3R87_RS02550 473126..474337 + 1212 WP_213674512.1 multidrug effflux MFS transporter -
J3R87_RS02555 474460..474933 - 474 WP_000456496.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T196588 WP_000482647.1 NZ_CP071594:c470295-470188 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T196588 NZ_CP095170:145577-145762 [Enterobacter roggenkampii]
GTGAAAAGTGCGGATGTCATTACTGTTCTGATCAGCCATGGCTGGAAATGTGTCAGAACGAAAGGAAGCCATCATCAGTT
TCGCCATCCCGAACAGAAAGGGCTGGTTACTGTCCCACATCCCAAGAAGGATATTAAACCGGGCACTCTCGCCCAGATCT
GGCGACAGGCGGGTATTAAACACTGA

Antitoxin


Download         Length: 61 bp

>AT196588 NZ_CP071594:470111-470171 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References