Detailed information of TA system TA196585

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 182422..182638
• Replicon: chromosome
• Accession: NZ_CP071594
• Organism: Staphylococcus aureus strain PNID0137

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: J3R87_RS01045
• Protein ID: WP_073392962.1
• Coordinates: 182534..182638 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	182422..182477 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J3R87_RS01025	177515..177835	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
J3R87_RS01030	177837..178817	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
J3R87_RS01035	179083..180174	+	1092	WP_000495684.1	hypothetical protein	-
J3R87_RS01040	180462..182108	+	1647	WP_042363653.1	IS1182-like element ISSau3 family transposase	-
-	182422..182477	+	56	-	-	Antitoxin
J3R87_RS01045	182534..182638	-	105	WP_073392962.1	hypothetical protein	Toxin
J3R87_RS01050	183318..183476	+	159	WP_001792784.1	hypothetical protein	-
J3R87_RS01055	184135..184992	-	858	WP_000370937.1	HAD family hydrolase	-
J3R87_RS01060	185060..185842	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	180462..182108	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T196585 WP_073392962.1 NZ_CP071594:c182638-182534 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T196585 NZ_CP095167:6424-6906 [Enterobacter roggenkampii]
GTGGGACGTATAACCACGCCCGAGCCGTTATCCAGCTCTCATCAGCTGGCTGAGTTCGTCAGTGGAGAGACAGTCCTCGA
TGAATGGCTAAAACAGAGAGGTTTAAAAAATCAAGCTCTTGGCGCTGCCCGAACGTTCGTTGTTTGCAAGACGGGTACGA
AGCAAGTAGCTGGTTTTTACTCTTTGGCCACCGGTAGCGTTAACCATACGGAAGCGACAGGTAGTCTTCGGCGTAACATG
CCAGATCCTATACCGGTGATTATACTCGCTCGCCTGGCGGTAGATGTCTCATTGCACGGAAAAGGGGTTGGCGCCGATTT
ACTCCACGATGCAGTGCTACGGTGTTATCGCGTAGCTGAGAACATTGGGGTTCGTGCGATAATGGTTCATGCGCTTACTG
AAGAAGCCAAAGGTTTCTATGCTCACCATGGATTTAAGGCATCACAAACTCATGAGAGGACTCTGTTTCTAAAGCTTCCA
TGA

Antitoxin

Nucleotide

• Length: 56 bp

>AT196585 NZ_CP071594:182422-182477 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin