Detailed information of TA system TA196578

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 2483724..2483882
• Replicon: chromosome
• Accession: NZ_CP071589
• Organism: Staphylococcus simiae strain 17941E

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: J3R86_RS11530
• Protein ID: WP_207517421.1
• Coordinates: 2483724..2483819 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2483844..2483882 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J3R86_RS11500	2479297..2479776	-	480	WP_207517415.1	hypothetical protein	-
J3R86_RS11505	2479992..2480438	+	447	WP_207517416.1	VOC family protein	-
J3R86_RS11510	2480596..2480979	-	384	WP_207517417.1	aspartate 1-decarboxylase	-
J3R86_RS11515	2480979..2481833	-	855	WP_207517418.1	pantoate--beta-alanine ligase	-
J3R86_RS11520	2481826..2482644	-	819	WP_207517419.1	3-methyl-2-oxobutanoate hydroxymethyltransferase	-
J3R86_RS11525	2482717..2483586	+	870	WP_207517420.1	oxidoreductase	-
J3R86_RS11530	2483724..2483819	+	96	WP_207517421.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2483844..2483882	-	39	-	-	Antitoxin
J3R86_RS11535	2484020..2484724	-	705	WP_207517422.1	acetolactate decarboxylase	-
J3R86_RS11540	2484989..2485948	-	960	WP_207517423.1	L-lactate dehydrogenase	-
J3R86_RS11545	2486492..2487940	+	1449	WP_207517424.1	amino acid permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3532.14 Da
• Isoelectric Point: 8.0320

>T196578 WP_207517421.1 NZ_CP071589:2483724-2483819 [Staphylococcus simiae]
MLETLVNTATTVISGCIIALFTHWLRNRNDK

Nucleotide

• Length: 96 bp

>T196578 NZ_CP095165:c278165-277863 [Enterobacter roggenkampii]
ATGAAGGAGATTGTTCAGACAGAATCCTTCCGACGCTGGGAGCAAAACTTAAAAGATCGACGAGCGAAGACCATTATCGC
TTCCCGCCTCTTTCGGTTGGCAAATGGCTTAGCGGGCGACGTTAAACCCGTGGGAGAAGGTATAAGTGAGCTAAGGATCC
ACTTTGGTCCGGGCTACAGGATCTATTTTAAAGACCAGGGCAATTACATCATCGTGCTGTTATGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTGATGGCAAAAATGCTGAGCAATGTATCCCAATGGCAGGAGTGA

Antitoxin

Nucleotide

• Length: 39 bp

>AT196578 NZ_CP071589:c2483882-2483844 [Staphylococcus simiae]
TATGCACCTAGTCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin