Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 183535..183757 Replicon chromosome
Accession NZ_CP071521
Organism Escherichia coli strain 11202

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag J2D70_RS00875 Protein ID WP_000141634.1
Coordinates 183650..183757 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 183535..183601 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J2D70_RS00855 178976..179878 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
J2D70_RS00860 179889..180872 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
J2D70_RS00865 180869..181873 + 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
J2D70_RS00870 181903..183174 - 1272 WP_001295225.1 aromatic amino acid transport family protein -
- 183535..183601 - 67 - - Antitoxin
J2D70_RS00875 183650..183757 + 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
J2D70_RS00880 183844..185523 - 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
J2D70_RS00885 185520..185711 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
J2D70_RS00890 185708..187279 - 1572 WP_001204931.1 cellulose biosynthesis c-di-GMP-binding protein BcsE -
J2D70_RS00895 187552..187740 + 189 WP_001063318.1 cellulose biosynthesis protein BcsR -
J2D70_RS00900 187776..188504 + 729 WP_011310329.1 cellulose biosynthesis protein BcsQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T196505 WP_000141634.1 NZ_CP071521:183650-183757 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T196505 NZ_CP095145:1918444-1918546 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 67 bp

>AT196505 NZ_CP071521:c183601-183535 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References