Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | ldrD-rdlD/Ldr(toxin) |
| Location | 330082..330303 | Replicon | chromosome |
| Accession | NZ_CP071441 | ||
| Organism | Escherichia coli strain EcPF20 | ||
Toxin (Protein)
| Gene name | ldrD | Uniprot ID | E0IV43 |
| Locus tag | J1F34_RS01650 | Protein ID | WP_000170926.1 |
| Coordinates | 330082..330189 (-) | Length | 36 a.a. |
Antitoxin (RNA)
| Gene name | rdlD | ||
| Locus tag | - | ||
| Coordinates | 330242..330303 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J1F34_RS01620 | 325391..326473 | + | 1083 | WP_000804726.1 | peptide chain release factor 1 | - |
| J1F34_RS01625 | 326473..327306 | + | 834 | WP_000456467.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
| J1F34_RS01630 | 327303..327695 | + | 393 | WP_000200392.1 | invasion regulator SirB2 | - |
| J1F34_RS01635 | 327699..328508 | + | 810 | WP_001257044.1 | invasion regulator SirB1 | - |
| J1F34_RS01640 | 328544..329398 | + | 855 | WP_000811065.1 | 3-deoxy-8-phosphooctulonate synthase | - |
| J1F34_RS01645 | 329547..329654 | - | 108 | WP_000170954.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
| - | 329702..329768 | + | 67 | NuclAT_49 | - | - |
| - | 329702..329768 | + | 67 | NuclAT_49 | - | - |
| - | 329702..329768 | + | 67 | NuclAT_49 | - | - |
| - | 329702..329768 | + | 67 | NuclAT_49 | - | - |
| - | 329702..329768 | + | 67 | NuclAT_52 | - | - |
| - | 329702..329768 | + | 67 | NuclAT_52 | - | - |
| - | 329702..329768 | + | 67 | NuclAT_52 | - | - |
| - | 329702..329768 | + | 67 | NuclAT_52 | - | - |
| - | 329702..329768 | + | 67 | NuclAT_55 | - | - |
| - | 329702..329768 | + | 67 | NuclAT_55 | - | - |
| - | 329702..329768 | + | 67 | NuclAT_55 | - | - |
| - | 329702..329768 | + | 67 | NuclAT_55 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_14 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_14 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_14 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_14 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_17 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_17 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_17 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_17 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_20 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_20 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_20 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_20 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_23 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_23 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_23 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_23 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_26 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_26 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_26 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_26 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_29 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_29 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_29 | - | - |
| - | 329704..329767 | + | 64 | NuclAT_29 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_32 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_32 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_32 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_32 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_35 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_35 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_35 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_35 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_38 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_38 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_38 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_38 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_41 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_41 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_41 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_41 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_44 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_44 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_44 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_44 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_47 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_47 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_47 | - | - |
| - | 329704..329769 | + | 66 | NuclAT_47 | - | - |
| J1F34_RS01650 | 330082..330189 | - | 108 | WP_000170926.1 | type I toxin-antitoxin system toxin Ldr family protein | Toxin |
| - | 330242..330303 | + | 62 | NuclAT_15 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_15 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_15 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_15 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_18 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_18 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_18 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_18 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_21 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_21 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_21 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_21 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_24 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_24 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_24 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_24 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_27 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_27 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_27 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_27 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_30 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_30 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_30 | - | Antitoxin |
| - | 330242..330303 | + | 62 | NuclAT_30 | - | Antitoxin |
| - | 330242..330304 | + | 63 | NuclAT_50 | - | - |
| - | 330242..330304 | + | 63 | NuclAT_50 | - | - |
| - | 330242..330304 | + | 63 | NuclAT_50 | - | - |
| - | 330242..330304 | + | 63 | NuclAT_50 | - | - |
| - | 330242..330304 | + | 63 | NuclAT_53 | - | - |
| - | 330242..330304 | + | 63 | NuclAT_53 | - | - |
| - | 330242..330304 | + | 63 | NuclAT_53 | - | - |
| - | 330242..330304 | + | 63 | NuclAT_53 | - | - |
| - | 330242..330304 | + | 63 | NuclAT_56 | - | - |
| - | 330242..330304 | + | 63 | NuclAT_56 | - | - |
| - | 330242..330304 | + | 63 | NuclAT_56 | - | - |
| - | 330242..330304 | + | 63 | NuclAT_56 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_33 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_33 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_33 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_33 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_36 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_36 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_36 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_36 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_39 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_39 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_39 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_39 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_42 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_42 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_42 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_42 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_45 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_45 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_45 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_45 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_48 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_48 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_48 | - | - |
| - | 330242..330305 | + | 64 | NuclAT_48 | - | - |
| J1F34_RS01655 | 330618..330725 | - | 108 | WP_000170965.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
| - | 330773..330838 | + | 66 | NuclAT_13 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_13 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_13 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_13 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_16 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_16 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_16 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_16 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_19 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_19 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_19 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_19 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_22 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_22 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_22 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_22 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_25 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_25 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_25 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_25 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_28 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_28 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_28 | - | - |
| - | 330773..330838 | + | 66 | NuclAT_28 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_31 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_31 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_31 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_31 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_34 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_34 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_34 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_34 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_37 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_37 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_37 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_37 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_40 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_40 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_40 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_40 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_43 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_43 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_43 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_43 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_46 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_46 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_46 | - | - |
| - | 330773..330840 | + | 68 | NuclAT_46 | - | - |
| - | 330774..330839 | + | 66 | NuclAT_51 | - | - |
| - | 330774..330839 | + | 66 | NuclAT_51 | - | - |
| - | 330774..330839 | + | 66 | NuclAT_51 | - | - |
| - | 330774..330839 | + | 66 | NuclAT_51 | - | - |
| - | 330774..330839 | + | 66 | NuclAT_54 | - | - |
| - | 330774..330839 | + | 66 | NuclAT_54 | - | - |
| - | 330774..330839 | + | 66 | NuclAT_54 | - | - |
| - | 330774..330839 | + | 66 | NuclAT_54 | - | - |
| - | 330774..330839 | + | 66 | NuclAT_57 | - | - |
| - | 330774..330839 | + | 66 | NuclAT_57 | - | - |
| - | 330774..330839 | + | 66 | NuclAT_57 | - | - |
| - | 330774..330839 | + | 66 | NuclAT_57 | - | - |
| J1F34_RS01660 | 331130..332230 | - | 1101 | WP_001295620.1 | sodium-potassium/proton antiporter ChaA | - |
| J1F34_RS01665 | 332500..332730 | + | 231 | WP_001146442.1 | putative cation transport regulator ChaB | - |
| J1F34_RS01670 | 332888..333583 | + | 696 | WP_001297117.1 | glutathione-specific gamma-glutamylcyclotransferase | - |
| J1F34_RS01675 | 333627..333980 | - | 354 | WP_001169669.1 | DsrE/F sulfur relay family protein YchN | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 3983.84 Da Isoelectric Point: 11.6501
>T196395 WP_000170926.1 NZ_CP071441:c330189-330082 [Escherichia coli]
MTLAKFAMIFWHDLAAPILAGIITAAIVGWWRNRK
MTLAKFAMIFWHDLAAPILAGIITAAIVGWWRNRK
Download Length: 108 bp
>T196395 NZ_CP095116:c968142-967681 [Staphylococcus aureus]
ATGGGATTATATGAAGAAACTTTAATACAACATGATTATATTGAAATAAGAGAGGCTGATGTGCTTCCAGATAATTTAGA
CGGGGTATGGTTAGGAGATTTAATTTTAATAAAGCGTGGTTTATCAGATAGAGAAAAAGCAGGAATTCTCTTCGAAGAAT
TAGCACATAATAAACTTACATACGGCGATATAGCCGATTACTCGAAGTTCAACAATCGCAAGTTCGAAAATTACGCACGT
AGACATGGCTTTATCTCAGCTGTTCCATTACGCGAAATTGTTGAAGCTTACAATTATGGCGTACGTAACTTGTATGAGTT
GTCCGAGTACCTACAACTAAGCGAAGAATACATATTAGAAGCAATAGAACAATATAAAAAGATATATGGTATTGGAACTC
ACTATGGCGAGTATTCAATTACATTTGAGCCGTTGAGAGTTTTTAAATATAAAGAAATATAA
ATGGGATTATATGAAGAAACTTTAATACAACATGATTATATTGAAATAAGAGAGGCTGATGTGCTTCCAGATAATTTAGA
CGGGGTATGGTTAGGAGATTTAATTTTAATAAAGCGTGGTTTATCAGATAGAGAAAAAGCAGGAATTCTCTTCGAAGAAT
TAGCACATAATAAACTTACATACGGCGATATAGCCGATTACTCGAAGTTCAACAATCGCAAGTTCGAAAATTACGCACGT
AGACATGGCTTTATCTCAGCTGTTCCATTACGCGAAATTGTTGAAGCTTACAATTATGGCGTACGTAACTTGTATGAGTT
GTCCGAGTACCTACAACTAAGCGAAGAATACATATTAGAAGCAATAGAACAATATAAAAAGATATATGGTATTGGAACTC
ACTATGGCGAGTATTCAATTACATTTGAGCCGTTGAGAGTTTTTAAATATAAAGAAATATAA
Antitoxin
Download Length: 62 bp
>AT196395 NZ_CP071441:330242-330303 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
