Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) fst-RNAII/-
Location 2493107..2493302 Replicon chromosome
Accession NZ_CP071172
Organism Enterococcus faecalis strain L13

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag JZP77_RS12015 Protein ID WP_015543884.1
Coordinates 2493107..2493202 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 2493237..2493302 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JZP77_RS11995 2488284..2489399 + 1116 WP_002377910.1 FAD-binding oxidoreductase -
JZP77_RS12000 2489468..2490622 - 1155 WP_002355280.1 mannitol-1-phosphate 5-dehydrogenase -
JZP77_RS12005 2490637..2491074 - 438 WP_002355279.1 PTS sugar transporter subunit IIA -
JZP77_RS12010 2491089..2492861 - 1773 WP_002391520.1 PTS mannitol transporter subunit IICBA -
JZP77_RS12015 2493107..2493202 + 96 WP_015543884.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2493237..2493302 - 66 - - Antitoxin
JZP77_RS12020 2493460..2493894 - 435 WP_002355276.1 PTS sugar transporter subunit IIA -
JZP77_RS12025 2493905..2495938 - 2034 WP_002355275.1 transcription antiterminator -
JZP77_RS12030 2495929..2497671 - 1743 WP_002401739.1 PTS transporter subunit EIIC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3659.47 Da        Isoelectric Point: 4.6275

>T195502 WP_015543884.1 NZ_CP071172:2493107-2493202 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Download         Length: 96 bp

>T195502 NZ_CP094745:c2496527-2496261 [Staphylococcus aureus]
ATGGTTAGGTTAAATATTACGTTTTCGCCTCAAGCCTTTGAAGATTATAAGTATTTTCAGCAGAACGATAAAAAAATGGT
GAAGAAGATTAATGAGTTAATTAAAAGTATTGACAGAAATGGTGCGTTGAAAGGTATAGGTAAGCCTGAAAAGTTAAAAT
CGAATCTGACTGGGTATTATAGTAGACGTATCAATCACGAACATAGATTGGTTTATACAGTAGATGACAATCATATAAAA
ATAGCATCATGTAAATACCATTATTAA

Antitoxin


Download         Length: 66 bp

>AT195502 NZ_CP071172:c2493302-2493237 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References