Detailed information of TA system TA195326

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2367444..2367628
• Replicon: chromosome
• Accession: NZ_CP071104
• Organism: Staphylococcus aureus strain PS/BAC/317/16/W

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: JYA73_RS11515
• Protein ID: WP_000482647.1
• Coordinates: 2367521..2367628 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2367444..2367504 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JYA73_RS11500 (JYA73_002303)	2362954..2363121	-	168	Protein_2233	hypothetical protein	-
JYA73_RS11505 (JYA73_002304)	2363352..2365085	-	1734	WP_000486505.1	ABC transporter ATP-binding protein	-
JYA73_RS11510 (JYA73_002305)	2365110..2366873	-	1764	WP_001064829.1	ABC transporter ATP-binding protein	-
-	2367444..2367504	+	61	-	-	Antitoxin
JYA73_RS11515 (JYA73_002306)	2367521..2367628	-	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
JYA73_RS11520 (JYA73_002307)	2367762..2368148	-	387	WP_000779351.1	flippase GtxA	-
JYA73_RS11525 (JYA73_002308)	2368416..2369558	+	1143	WP_001176855.1	glycerate kinase	-
JYA73_RS11530 (JYA73_002309)	2369618..2370277	+	660	WP_211021896.1	hypothetical protein	-
JYA73_RS11535 (JYA73_002310)	2370459..2371670	+	1212	WP_001191919.1	multidrug effflux MFS transporter	-
JYA73_RS11540 (JYA73_002311)	2371793..2372266	-	474	WP_000456496.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T195326 WP_000482647.1 NZ_CP071104:c2367628-2367521 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T195326 NZ_CP094532:c1273194-1272910 [Chryseobacterium suipulveris]
ATGGATATTTCAAAATTTGACATTGCAGATTATTTGGACAGCAACGAAATGATTGCTGAATATCTTAATGTTGTCCTTGA
AGAAGGCGATGATTCTGAAATTGTTGTAGCAATTGGTAATATTGCAAAAGCAATCGGAATGACAAAAATTGCAGAAGAAA
CAGGAATGAGCAGACCGAGTTTGTACAAAGCACTTTCTGAAGGTGCAAAACCACAGTTTTCAACAATTATGAAAGTTTTG
AAAGCAGTTGGCGGACAAATAAGAGTTAATCCTATAACTGCATAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT195326 NZ_CP071104:2367444-2367504 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin