Detailed information of TA system TA195316

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2566503..2566781
• Replicon: chromosome
• Accession: NZ_CP071102
• Organism: Staphylococcus aureus strain CI/BAC/25/13/W

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: JYA70_RS12625
• Protein ID: WP_001802298.1
• Coordinates: 2566503..2566607 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	2566603..2566781 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JYA70_RS12610	2563300..2564082	+	783	WP_000908175.1	ABC transporter ATP-binding protein	-
JYA70_RS12615	2564150..2565007	+	858	WP_000370925.1	Cof-type HAD-IIB family hydrolase	-
JYA70_RS12620	2565665..2565823	-	159	WP_001792784.1	hypothetical protein	-
JYA70_RS12625	2566503..2566607	+	105	WP_001802298.1	hypothetical protein	Toxin
-	2566603..2566781	-	179	-	-	Antitoxin
JYA70_RS12630	2567049..2568140	-	1092	WP_000495682.1	hypothetical protein	-
JYA70_RS12635	2568406..2569386	-	981	WP_000019744.1	CDF family zinc efflux transporter CzrB	-
JYA70_RS12640	2569388..2569708	-	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
JYA70_RS12645	2569860..2570525	+	666	WP_001024095.1	SDR family oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T195316 WP_001802298.1 NZ_CP071102:2566503-2566607 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T195316 NZ_CP094525:c3437496-3437095 [Bradyrhizobium sp. ISRA463]
GTGACGCGCTACCTGCTCGACACCAACATCATTTCCGACCTCGTCAGAAATCCGCAAGGCAAGGTGGCGAAGCGGATCGC
AAAGGTTGGCGAGGCCAATGTCTGCACAAGCATCATTGTCGCGTCCGAACTGCGCTACGGCTGTGCGAAGGCCGGATCGC
CACGGCTCACCAAAGCCGTCGAGGAGATTCTTGGCGAGATCCCCGTGCTGCCCTTCGATGTTCCCGCCGACGCAGAATAC
GGGGTTGTCCGCTCAGAACTGGAAGCTGCCGGAAAGCCGATTGGTAGCAACGATCTCCTGATCGCTGCGCACGCCTCCGC
ATTGAGCATGACTATCGTGACCGCCAATACCGACGAGTTCAAACGAGCCCGTGGCTTAAAAGTCACCAACTGGCTTGATT
GA

Antitoxin

Nucleotide

• Length: 179 bp

>AT195316 NZ_CP071102:c2566781-2566603 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin