Detailed information of TA system TA195311

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/Txe-RelB
• Location: 2259413..2259936
• Replicon: chromosome
• Accession: NZ_CP071102
• Organism: Staphylococcus aureus strain CI/BAC/25/13/W

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: T1YCD0
• Locus tag: JYA70_RS11050
• Protein ID: WP_000074043.1
• Coordinates: 2259670..2259936 (+)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: T1YBB2
• Locus tag: JYA70_RS11045
• Protein ID: WP_000587618.1
• Coordinates: 2259413..2259670 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (4-87)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-68)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10657.45 Da
• Isoelectric Point: 10.3584

>T195311 WP_000074043.1 NZ_CP071102:2259670-2259936 [Staphylococcus aureus]
MSNYTVKIKNSAKLDLKKIKHPYLKKTFIEIVETLKNNPYKITQSFEKLEPKYLERYSRRINLQHRVVYTIDDRNKVVLI
LSAWSHYD

Nucleotide

• Length: 267 bp

>T195311 NZ_CP094521:4296630-4297031 [Bradyrhizobium sp. ISRA437]
ATGCCCGGTGACTTCTTCGACACCAACGTGCTTGTCCACCTCGCGTCGGGCGATCCCTTGAAGGCCGATCGGGCAGAAGC
CGTCATTTCCCGGGGCGGGGTGATTAGCGTTCAGGTGCTGAATGAAATCGCCAATGTCGCGCGCCGCAAGATGCGGATGT
CATGGACGGAGACGCGCGCATTTCTGACGATCTTGCGCAATCTGCTGACGATCTATCCCCTCACGCAGGAGATCCATGAC
GCTGGACTTGATCTGGCCGAGCGCTACGGATTGTCGATGTTCGACGCCATGATCGCCGCCTCCGCGCTTCAGGCCGGTTG
CGACAGATTGTGGTCTGAGGACATGCAGCACAACCAAGTCCTGGATAACAGCCTTCGGATCGTCAATCCGTTTCGGGTCT
AG

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9762.78 Da
• Isoelectric Point: 4.1958

>AT195311 WP_000587618.1 NZ_CP071102:2259413-2259670 [Staphylococcus aureus]
MIITSPTEARKDFYQLLKNVNNNHEPIYISGNNAENNAVIIGLEDWKSIQETMYLVSTGTMDKVREREKDNSGTTNIDDI
DWDNL

Nucleotide

• Length: 258 bp

>AT195311 NZ_CP094521:4296410-4296640 [Bradyrhizobium sp. ISRA437]
ATGCAAGTCGCCAAATGGGGTAACAGCCTCGCGATTCGGCTTCCCGCGGCCGTGGTCGAAGCGCTCGAACTCAAGGAAGG
CGACGAGATCGAAATCCATGTTGCCGACGAGCGGAACTTCGGCGTCGCGCGCAAACCGGGGCGTGAGGAGTTACTGGCGC
GACTGCGCGCCTTCCGCGGACGCCTGCCGGCGGATTTCAAATTCGACCGGGACGAGGCAAATGCCCGGTGA

Structures

Toxin

• AlphaFold DB: T1YCD0

Antitoxin

• AlphaFold DB: T1YBB2