Detailed information of TA system TA195308

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 167735..167915
• Replicon: chromosome
• Accession: NZ_CP071102
• Organism: Staphylococcus aureus strain CI/BAC/25/13/W

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: JYA70_RS01055
• Protein ID: WP_001801861.1
• Coordinates: 167820..167915 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	167735..167792 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JYA70_RS01025	164088..165206	+	1119	WP_000072558.1	restriction endonuclease subunit S	-
JYA70_RS01030	165852..166295	+	444	WP_000742594.1	DUF1433 domain-containing protein	-
JYA70_RS01035	166574..166852	+	279	WP_001798632.1	DUF1433 domain-containing protein	-
JYA70_RS01040	166874..167248	+	375	WP_211044217.1	DUF1433 domain-containing protein	-
JYA70_RS01045	167436..167618	+	183	Protein_169	transposase	-
JYA70_RS01050	167596..167697	-	102	WP_001791232.1	hypothetical protein	-
-	167735..167792	+	58	-	-	Antitoxin
JYA70_RS01055	167820..167915	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
JYA70_RS01060	168366..168812	+	447	WP_000747802.1	DUF1433 domain-containing protein	-
JYA70_RS01065	169497..169880	+	384	WP_000070811.1	hypothetical protein	-
JYA70_RS01070	169891..170067	+	177	WP_000375476.1	hypothetical protein	-
JYA70_RS01075	170367..170995	+	629	Protein_175	ImmA/IrrE family metallo-endopeptidase	-
JYA70_RS01080	171193..171765	-	573	WP_000414212.1	hypothetical protein	-
JYA70_RS01085	171866..172207	-	342	WP_000627548.1	DUF3969 family protein	-
JYA70_RS01090	172248..172874	-	627	WP_000669019.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	146045..175436	29391

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T195308 WP_001801861.1 NZ_CP071102:c167915-167820 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T195308 NZ_CP094519:4298062-4298463 [Bradyrhizobium sp. ISRA436]
ATGCCCGGTGACTTCTTCGACACCAACGTGCTTGTCCACCTCGCGTCGGGCGATCCCTTGAAGGCCGATCGGGCAGAAGC
CGTCATTTCCCGGGGCGGGGTGATTAGCGTTCAGGTGCTGAATGAAATCGCCAATGTCGCGCGCCGCAAGATGCGGATGT
CATGGACGGAGACGCGCGCATTTCTGACGATCTTGCGCAATCTGCTGACGATCTATCCCCTCACGCAGGAGATCCATGAC
GCTGGACTTGATCTGGCCGAGCGCTACGGATTGTCGATGTTCGACGCCATGATCGCCGCCTCCGCGCTTCAGGCCGGTTG
CGACAGATTGTGGTCTGAGGACATGCAGCACAACCAAGTCCTGGATAACAGCCTTCGGATCGTCAATCCGTTTCGGGTCT
AG

Antitoxin

Nucleotide

• Length: 58 bp

>AT195308 NZ_CP071102:167735-167792 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin