Detailed information of TA system TA195293

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1887841..1888021
• Replicon: chromosome
• Accession: NZ_CP071100
• Organism: Staphylococcus aureus strain PS/BAC/169/17/W

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: JYA66_RS09110
• Protein ID: WP_001801861.1
• Coordinates: 1887841..1887936 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1887964..1888021 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JYA66_RS09080	1882982..1883608	+	627	WP_000669027.1	hypothetical protein	-
JYA66_RS09085	1883649..1883990	+	342	WP_000627537.1	DUF3969 family protein	-
JYA66_RS09090	1884091..1884663	+	573	WP_000414214.1	hypothetical protein	-
JYA66_RS09095	1885020..1886180	-	1161	WP_247655139.1	FRG domain-containing protein	-
JYA66_RS13750	1886180..1886446	-	267	WP_247655149.1	ImmA/IrrE family metallo-endopeptidase	-
JYA66_RS13755	1886454..1886750	-	297	WP_247655140.1	ImmA/IrrE family metallo-endopeptidase	-
JYA66_RS09105	1886943..1887390	-	448	Protein_1805	DUF1433 domain-containing protein	-
JYA66_RS09110	1887841..1887936	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1887964..1888021	-	58	-	-	Antitoxin
JYA66_RS09115	1888059..1888160	+	102	WP_001791232.1	hypothetical protein	-
JYA66_RS09120	1888335..1888778	-	444	WP_211020161.1	DUF1433 domain-containing protein	-
JYA66_RS09125	1888778..1889222	-	445	Protein_1809	DUF1433 domain-containing protein	-
JYA66_RS09130	1889222..1889665	-	444	WP_211020163.1	DUF1433 domain-containing protein	-
JYA66_RS09135	1890190..1892613	+	2424	WP_211020165.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T195293 WP_001801861.1 NZ_CP071100:1887841-1887936 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T195293 NZ_CP094481:c1980-1645 [Klebsiella pneumoniae]
ATGGAATACTACGAATTTGTAGAAACCTCTGTGTTCACGCGAGAGATGAAAACTCTACTCAGTGATGATGAATACAAAGA
GTTTCAAACGTTCCTCATCGAGAACCCGGAGGCGGGTGATCTGATTGTAGGAACTGGCGGTTGTCGCAAGGTTAGATGGT
CACGGCAGGGAACAGGTAAAAGTTCAGGTGTCCGTGCTATTTACTACTTCTACAACCCGGCAGGGCGCTTATACATGCTT
ATCATCTATCCAAAGAGTGAGAAGGATAGTTTGACAGCAGCAGAGAAAAACCAGCTCAAAGCGGTTGTAGCGGGTTTTAA
AGGTGAAGAGGGCTAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT195293 NZ_CP071100:c1888021-1887964 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin