Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 2649713..2650407 Replicon chromosome
Accession NZ_CP071062
Organism Dickeya solani strain IPO2019

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag JYR06_RS11700 Protein ID WP_026594479.1
Coordinates 2649713..2650111 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID A0A2K8VUD1
Locus tag JYR06_RS11705 Protein ID WP_022633740.1
Coordinates 2650114..2650407 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JYR06_RS11670 2644893..2645927 - 1035 WP_022633732.1 harpin HrpZ family protein -
JYR06_RS11675 2646088..2646498 - 411 WP_022633733.1 hypothetical protein -
JYR06_RS11680 2646495..2646683 - 189 WP_022633734.1 hypothetical protein -
JYR06_RS11685 2646718..2648787 - 2070 WP_023637836.1 type III secretion system outer membrane ring subunit SctC -
JYR06_RS11690 2648780..2649214 - 435 WP_022633737.1 hypothetical protein -
JYR06_RS11695 2649201..2649428 - 228 WP_022633738.1 type III secretion protein HrpF -
JYR06_RS11700 2649713..2650111 - 399 WP_026594479.1 type II toxin-antitoxin system YafO family toxin Toxin
JYR06_RS11705 2650114..2650407 - 294 WP_022633740.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
JYR06_RS11710 2650625..2651674 - 1050 WP_022633741.1 hypothetical protein -
JYR06_RS11715 2652214..2653374 + 1161 WP_022633742.1 alpha/beta fold hydrolase -
JYR06_RS11720 2653385..2654698 - 1314 WP_022633743.1 lytic murein transglycosylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2649713..2659129 9416


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(27-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15230.56 Da        Isoelectric Point: 8.4931

>T195160 WP_026594479.1 NZ_CP071062:c2650111-2649713 [Dickeya solani]
IRIFKSTLIRQQLSQQELDDLVADFHAYKQNGVLPDTFGRDAPYDDDRTYPLVKAEQVAHIHLADADAPFPRFLRQFKRT
SDRAHLVYCQGAMDPEACLLIIILKPEAHKMARNNNNMHKIGMMAAAFRMKY

Download         Length: 399 bp

>T195160 NZ_CP094339:2867379-2867486 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10934.48 Da        Isoelectric Point: 5.2082

>AT195160 WP_022633740.1 NZ_CP071062:c2650407-2650114 [Dickeya solani]
MERILAEKSINITELRKNPAKYFIDEPVAVLSNNRPAGYMVSAKVFEELIDLLEAKQETVHTVARFRPTAERLRALADSG
QKLLNDASGKDLTEFTE

Download         Length: 294 bp

>AT195160 NZ_CP094339:c2867326-2867265 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2K8VUD1

References