Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2337816..2338000 Replicon chromosome
Accession NZ_CP070991
Organism Staphylococcus aureus strain CBS2016-05

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag JYA46_RS11535 Protein ID WP_000482647.1
Coordinates 2337816..2337923 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2337940..2338000 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JYA46_RS11510 2333177..2333650 + 474 WP_000456493.1 GyrI-like domain-containing protein -
JYA46_RS11515 2333773..2334984 - 1212 WP_001191927.1 multidrug effflux MFS transporter -
JYA46_RS11520 2335167..2335826 - 660 WP_000831298.1 membrane protein -
JYA46_RS11525 2335886..2337028 - 1143 WP_031906099.1 glycerate kinase -
JYA46_RS11530 2337296..2337682 + 387 WP_000779353.1 flippase GtxA -
JYA46_RS11535 2337816..2337923 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2337940..2338000 - 61 - - Antitoxin
JYA46_RS11540 2338627..2340390 + 1764 WP_098818016.1 ABC transporter ATP-binding protein -
JYA46_RS11545 2340415..2342148 + 1734 Protein_2248 ABC transporter ATP-binding protein -
JYA46_RS11550 2342379..2342546 + 168 WP_072491235.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T194952 WP_000482647.1 NZ_CP070991:2337816-2337923 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T194952 NZ_CP094238:c1955671-1955495 [Comamonas sp. 7D-2]
ATGAAGCAAAGCGAGTTCCAGAGATGGCTCGCTGCGCAGGGAGCAACTTTCAGCCACGGCACACGCCACTTGAAGGTTTT
CCTGAACGGCAAGCAAACAATAATGCCCCGGCACCCAAGCCAAGAGATTGGCGAAGGACTCAGAAAAGCGATTCTGAAAC
AGCTAGGACTTAAATAG

Antitoxin


Download         Length: 61 bp

>AT194952 NZ_CP070991:c2338000-2337940 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References