Detailed information of TA system TA194947

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 206549..206729
• Replicon: chromosome
• Accession: NZ_CP070991
• Organism: Staphylococcus aureus strain CBS2016-05

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: JYA46_RS01365
• Protein ID: WP_001801861.1
• Coordinates: 206634..206729 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	206549..206606 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JYA46_RS01340	202222..202950	+	729	WP_098817909.1	staphylococcal enterotoxin type I	-
JYA46_RS01345	203104..203889	+	786	WP_098817908.1	staphylococcal enterotoxin type U	-
JYA46_RS01350	203928..204683	+	756	WP_072491894.1	staphylococcal enterotoxin type N	-
JYA46_RS01355	204974..205749	+	776	Protein_233	staphylococcal enterotoxin type G	-
JYA46_RS01360	206440..206511	-	72	Protein_234	hypothetical protein	-
-	206549..206606	+	58	-	-	Antitoxin
JYA46_RS01365	206634..206729	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
JYA46_RS01370	206939..207109	+	171	WP_072491905.1	IS3 family transposase	-
JYA46_RS01375	207483..207809	+	327	WP_072491904.1	hypothetical protein	-
JYA46_RS01380	207820..207996	+	177	WP_000375476.1	hypothetical protein	-
JYA46_RS01385	207998..208183	+	186	WP_000809743.1	hypothetical protein	-
JYA46_RS01390	208513..209085	-	573	WP_000414223.1	hypothetical protein	-
JYA46_RS01395	209186..209527	-	342	WP_000627546.1	DUF3969 family protein	-
JYA46_RS01400	209568..210194	-	627	WP_072491897.1	hypothetical protein	-
JYA46_RS01405	210270..211265	-	996	WP_210994231.1	DUF4352 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T194947 WP_001801861.1 NZ_CP070991:c206729-206634 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T194947 NZ_CP094237:c4748517-4747984 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGTGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAAGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT194947 NZ_CP070991:206549-206606 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin