Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 4701118..4701722 Replicon chromosome
Accession NZ_CP070982
Organism Pseudomonas entomophila strain Small

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag JYG34_RS20550 Protein ID WP_213658088.1
Coordinates 4701118..4701438 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag JYG34_RS20555 Protein ID WP_213658089.1
Coordinates 4701435..4701722 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JYG34_RS20525 (JYG34_20525) 4696608..4696829 + 222 WP_213658084.1 cysteine-rich CWC family protein -
JYG34_RS20530 (JYG34_20530) 4696862..4697620 + 759 WP_213658085.1 pseudouridine synthase -
JYG34_RS20535 (JYG34_20535) 4698007..4698891 + 885 WP_213658086.1 alpha/beta fold hydrolase -
JYG34_RS20545 (JYG34_20545) 4699268..4700968 + 1701 WP_213658087.1 SulP family inorganic anion transporter -
JYG34_RS20550 (JYG34_20550) 4701118..4701438 + 321 WP_213658088.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JYG34_RS20555 (JYG34_20555) 4701435..4701722 + 288 WP_213658089.1 NadS family protein Antitoxin
JYG34_RS20560 (JYG34_20560) 4701761..4702243 - 483 WP_213658090.1 hypothetical protein -
JYG34_RS20565 (JYG34_20565) 4702258..4702629 - 372 WP_249746185.1 hypothetical protein -
JYG34_RS20570 (JYG34_20570) 4702726..4704315 - 1590 WP_249746186.1 alpha/beta hydrolase-fold protein -
JYG34_RS20575 (JYG34_20575) 4704323..4706689 - 2367 WP_213658092.1 TonB-dependent receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-87)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12119.03 Da        Isoelectric Point: 9.9587

>T194908 WP_213658088.1 NZ_CP070982:4701118-4701438 [Pseudomonas entomophila]
MLFSETVIFTKRVKELLDDETYRLLQVRLLIAPDAGDLIEGTGGLRKLRIAANGHGKRGGARVIYYHFNAAAQIAMLYIY
PKNEQQDLSTEQRKALKAVIEHWRHP

Download         Length: 321 bp

>T194908 NZ_CP094177:18386-19168 [Helicobacter pylori]
ATGGAAATTAAAGAAGAGGATAAAGATAAAAAGCTAGAAAAAATTATTGTATTGCTGTGCGAAGAGGGGGATTTGTCTAG
CCAAAAAGATCAAATCATCAAAGATCTCAAAGAAATCTATAAAGGAGAATACAAGCATAAATACTCAAAAATCACAACTA
TTATTTTAAATTCCACAAGGGATAAAGAGCAAGCCTTTATGATGCTCACACAAAATATAAAGACACTCAAAGAGATTCAA
GATAATAAAGAAGTTGAAAGCATTAAACCAAAACTAGAAAAGCTTTATGATCACATGAATTTAGAGTGTATCAGACTGCA
AGATTTTGATGAGAAAATGAGTAGAGTTAAAAATGTTTCTATAAAGTTAGAAGATGAACTAAATAAAAACTATAAAAAAT
TAAGCGAAGAATTGAATAAGCAACAAACACAATACATAACAATTCTAGGTATTTTTGCCTCTATTGTTTTAACATTTGTT
GGGGGATTGGCGTTTTCCACTTCTGTTTTATCAAATATTGACAAAGCGAACGCCTATCGTTTGGTTTTTGTTATGGCTTT
TATAGCTTTATTTTTTGGGAATATTTTGTATCGGCTTTTTTCTTTTTTATCAAAAATATCCTTATCAGAAGAGAAAAAAG
ATAAACAAGAAAATTTTTTCAAAAAACTTATTTTTTGGTTTAATCTAATGGTTATAATTCTATTTGTGATTGGTTTTGTG
GGAGAGAGAATTGATGGGCAATACAAAGCTCAGATTTCTAAAGATTTTAAAAGACCAAGATAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 11093.69 Da        Isoelectric Point: 8.9507

>AT194908 WP_213658089.1 NZ_CP070982:4701435-4701722 [Pseudomonas entomophila]
MSRFFEELMQSVEQMDEIIQGQRQPSRQFEIDALQVRNIRKRTGLSQVRFAEMIDVQVATLRNWEQGRREPTGPAKALLR
ALHNDPEHVLKALAH

Download         Length: 288 bp

>AT194908 NZ_CP094177:17959-18396 [Helicobacter pylori]
ATGGTCAATACTTTGGAATTAGCAAAATATATTCTTAAGCATTCAAACAAAGAATTGAGCAACTTAGAATTGCAAAAAAC
TTTGTATTTCACAGAGCTTGACTATATTAAAAAGTTTGACAAACACCTAGTTTCTGATGATTTTGAAGCTTGGAAATATG
GGCCTGTTGCAAGAGAAGTGTATTATGAATATCGCAATTATGGTGCCAATTCTATTGACAAACCTAAAGAAGAAACGCTC
TCACAAAATCTTAGAGAAGATGAACTTGAAACCATCAATCGCTCCATAGAAAAATGCAACGAAAAATCCTATTGGGATTT
AGTGAAAGAGAGTCATAAAGAAGATGGTGCTTGGCATAAAAGCTTCAAAGAAGATAGAAAAGAAATCATTAGCAAAGATT
TGATAAAACAAGAAGCAAAACAAGCAAATGGAAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References