Detailed information of TA system TA194884

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-as-bsrE/-
• Location: 2258961..2259178
• Replicon: chromosome
• Accession: NZ_CP070976
• Organism: Bacillus halotolerans strain MBH1

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: JYG31_RS11475
• Protein ID: WP_014470124.1
• Coordinates: 2258961..2259137 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2259078..2259178 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JYG31_RS11455 (2254933)	2254933..2256801	-	1869	WP_213417640.1	hypothetical protein	-
JYG31_RS11460 (2257141)	2257141..2258373	-	1233	WP_213417642.1	hypothetical protein	-
JYG31_RS11465 (2258455)	2258455..2258646	-	192	WP_213417644.1	hypothetical protein	-
JYG31_RS11470 (2258691)	2258691..2258942	-	252	WP_213417645.1	hypothetical protein	-
JYG31_RS11475 (2258961)	2258961..2259137	-	177	WP_014470124.1	hypothetical protein	Toxin
- (2259078)	2259078..2259178	+	101	NuclAT_0	-	Antitoxin
- (2259078)	2259078..2259178	+	101	NuclAT_0	-	Antitoxin
- (2259078)	2259078..2259178	+	101	NuclAT_0	-	Antitoxin
- (2259078)	2259078..2259178	+	101	NuclAT_0	-	Antitoxin
JYG31_RS11480 (2260150)	2260150..2260344	+	195	WP_072692657.1	hypothetical protein	-
JYG31_RS11485 (2260384)	2260384..2262900	+	2517	WP_213417646.1	hypothetical protein	-
JYG31_RS11490 (2263157)	2263157..2263432	+	276	WP_053574266.1	HU family DNA-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2183059..2319229	136170

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (3-88)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6856.40 Da
• Isoelectric Point: 12.8849

>T194884 WP_014470124.1 NZ_CP070976:c2259137-2258961 [Bacillus halotolerans]
VLEKVGIIVAFLISLTVLTINSLTIVEKIRNLKNGTSKKKKRTRKRLRSKRQRKRIRR

Nucleotide

• Length: 177 bp

>T194884 NZ_CP094151:579373-579639 [Helicobacter pylori]
GTGTTAAAACTCAATCTTAAAAAATCTTTTCAAAAAGATTTTGATAAATTACTTTTGAATGGGTTTGATGATAGCGTTTT
GAATGAAGTCATTCTAACCTTAAGAAAGAAAGAACCATTATCCCCACAATTTCAAGATCATGCCTTAAAGGGAAAATGGA
AACCTTTTAGGGAATACCACATCAAAGCCGATATTTTGCTTGTGTATTTGGTGAAAGATGATGAACTGATTTTGTTAAGG
TTGGGCAGTCATAGCGAGCTGTTTTAA

Antitoxin

Nucleotide

• Length: 101 bp

>AT194884 NZ_CP070976:2259078-2259178 [Bacillus halotolerans]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTATGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Structures

Antitoxin