Detailed information of TA system TA194878

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 2258691..2259020
• Replicon: chromosome
• Accession: NZ_CP070976
• Organism: Bacillus halotolerans strain MBH1

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: JYG31_RS11470
• Protein ID: WP_213417645.1
• Coordinates: 2258691..2258942 (-)
• Length: 84 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	2258920..2259020 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JYG31_RS11455	2254933..2256801	-	1869	WP_213417640.1	hypothetical protein	-
JYG31_RS11460	2257141..2258373	-	1233	WP_213417642.1	hypothetical protein	-
JYG31_RS11465	2258455..2258646	-	192	WP_213417644.1	hypothetical protein	-
JYG31_RS11470	2258691..2258942	-	252	WP_213417645.1	hypothetical protein	Toxin
-	2258920..2259020	+	101	-	-	Antitoxin
JYG31_RS11475	2258961..2259137	-	177	WP_014470124.1	hypothetical protein	-
-	2259078..2259178	+	101	NuclAT_0	-	-
-	2259078..2259178	+	101	NuclAT_0	-	-
-	2259078..2259178	+	101	NuclAT_0	-	-
-	2259078..2259178	+	101	NuclAT_0	-	-
JYG31_RS11480	2260150..2260344	+	195	WP_072692657.1	hypothetical protein	-
JYG31_RS11485	2260384..2262900	+	2517	WP_213417646.1	hypothetical protein	-
JYG31_RS11490	2263157..2263432	+	276	WP_053574266.1	HU family DNA-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2183059..2319229	136170

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Virulence-associated protein D / CRISPR associated protein Cas2 (1-87)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 10149.20 Da
• Isoelectric Point: 10.0301

>T194878 WP_213417645.1 NZ_CP070976:c2258942-2258691 [Bacillus halotolerans]
MNFSFSSYPYYNMIKHIVNMKRFSLWFTHITFIGLFLMFQLIKDYFSSEAQTLINTIFVVTCIIIFLIWIIYFVFLKLRN
KSH

Nucleotide

• Length: 252 bp

>T194878 NZ_CP094147:592510-592794 [Helicobacter pylori]
ATGTATGCTTTAGCGTTTGATTTAAAGATTGAGATTTTAAAAAAAGAATACGGAGAACCCTACAATAAAGCCTATGATGA
TTTAAGGCAAGAATTAGAGCTATTAGGGTTTGAATGGACTCAAGGGAGCGTTTATGTTAATTATTCTAAAGAAAACACTC
TAGCACAAGTCTATAAAGCGATCAATAAACTCTCTCAAATTGAGTGGTTTAAAAAGTCTGTTAGGGATATTAGAGCGTTT
AAGGTAGAGGACTTTAGCGATTTCACTGAGATTGTGAAATCCTAG

Antitoxin

Nucleotide

• Length: 101 bp

>AT194878 NZ_CP070976:2258920-2259020 [Bacillus halotolerans]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTGGTACTCATCTGCGTATACGTTTGCGTTGCCTCTTGCTACGGAG
TCGCTTACGTGTACGCTTTTT

Structures

Antitoxin