Detailed information of TA system TA194844

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 949791..949952
• Replicon: chromosome
• Accession: NZ_CP070964
• Organism: Staphylococcus sp. SB1-57

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: JX000_RS04780
• Protein ID: WP_015364873.1
• Coordinates: 949791..949886 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	949918..949952 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JX000_RS04770	945765..948698	+	2934	WP_206140941.1	AAA family ATPase	-
JX000_RS04775	948698..949639	+	942	WP_002452110.1	3'-5' exoribonuclease YhaM	-
JX000_RS04780	949791..949886	+	96	WP_015364873.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	949918..949952	-	35	-	-	Antitoxin
JX000_RS04785	950038..951030	-	993	WP_124227921.1	peptidylprolyl isomerase	-
JX000_RS04790	951450..952007	-	558	WP_002452113.1	DUF3267 domain-containing protein	-
JX000_RS04795	952201..952572	-	372	WP_002452114.1	YtxH domain-containing protein	-
JX000_RS04800	952650..953075	-	426	WP_049424853.1	HIT family protein	-
JX000_RS04805	953207..953947	+	741	WP_002452116.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Virulence-associated protein D / CRISPR associated protein Cas2 (1-87)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3610.26 Da
• Isoelectric Point: 8.0878

>T194844 WP_015364873.1 NZ_CP070964:949791-949886 [Staphylococcus sp. SB1-57]
MTEIFVHIATTVISGCIVTLFAHWLRHRNDK

Nucleotide

• Length: 96 bp

>T194844 NZ_CP094120:619201-619485 [Helicobacter pylori]
ATGTATGCTTTAGCGTTTGATTTAAAGATTGAGATTTTAAAAAAAGAATACGGAGAACCCTACAATAAAGCCTATGATGA
TTTAAGGCAAGAATTAGAGCTATTAGGGTTTGAATGGACTCAAGGGAGCGTTTATGTTAATTATTCTAAAGAAAACACTC
TAGCACAAGTCTATAAAGCGATCAATAAACTCTCTCAAATTGAGTGGTTTAAAAAGTCTGTTAGGGATATTAGAGCGTTT
AAGGTAGAGGACTTTAGCGATTTTACTGAGATTGTGAAATCCTAG

Antitoxin

Nucleotide

• Length: 35 bp

>AT194844 NZ_CP070964:c949952-949918 [Staphylococcus sp. SB1-57]
ACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin