Detailed information of TA system TA194755

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-sokX/Ldr(toxin)
• Location: 330652..330871
• Replicon: chromosome
• Accession: NZ_CP070954
• Organism: Escherichia fergusonii strain EF44

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: -
• Locus tag: JYG65_RS01515
• Protein ID: WP_223666505.1
• Coordinates: 330764..330871 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	sokX
Locus tag	-
Coordinates	330652..330715 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JYG65_RS01490 (325876)	325876..327087	+	1212	WP_000256500.1	sigma 54-interacting transcriptional regulator	-
JYG65_RS01495 (327103)	327103..328401	-	1299	WP_001152711.1	amino acid permease	-
JYG65_RS01500 (328650)	328650..329846	-	1197	WP_001016304.1	methionine gamma-lyase	-
JYG65_RS01510 (330282)	330282..330389	+	108	WP_002431793.1	type I toxin-antitoxin system toxin Ldr family protein	-
- (330650)	330650..330715	-	66	NuclAT_11	-	-
- (330650)	330650..330715	-	66	NuclAT_11	-	-
- (330650)	330650..330715	-	66	NuclAT_11	-	-
- (330650)	330650..330715	-	66	NuclAT_11	-	-
- (330650)	330650..330715	-	66	NuclAT_12	-	-
- (330650)	330650..330715	-	66	NuclAT_12	-	-
- (330650)	330650..330715	-	66	NuclAT_12	-	-
- (330650)	330650..330715	-	66	NuclAT_12	-	-
- (330652)	330652..330715	-	64	NuclAT_13	-	Antitoxin
- (330652)	330652..330715	-	64	NuclAT_13	-	Antitoxin
- (330652)	330652..330715	-	64	NuclAT_13	-	Antitoxin
- (330652)	330652..330715	-	64	NuclAT_13	-	Antitoxin
- (330652)	330652..330715	-	64	NuclAT_14	-	Antitoxin
- (330652)	330652..330715	-	64	NuclAT_14	-	Antitoxin
- (330652)	330652..330715	-	64	NuclAT_14	-	Antitoxin
- (330652)	330652..330715	-	64	NuclAT_14	-	Antitoxin
- (330652)	330652..330715	-	64	NuclAT_15	-	Antitoxin
- (330652)	330652..330715	-	64	NuclAT_15	-	Antitoxin
- (330652)	330652..330715	-	64	NuclAT_15	-	Antitoxin
- (330652)	330652..330715	-	64	NuclAT_15	-	Antitoxin
- (330652)	330652..330715	-	64	NuclAT_16	-	Antitoxin
- (330652)	330652..330715	-	64	NuclAT_16	-	Antitoxin
- (330652)	330652..330715	-	64	NuclAT_16	-	Antitoxin
- (330652)	330652..330715	-	64	NuclAT_16	-	Antitoxin
JYG65_RS01515 (330764)	330764..330871	+	108	WP_223666505.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
JYG65_RS01520 (331245)	331245..331352	+	108	WP_114091462.1	type I toxin-antitoxin system toxin Ldr family protein	-
JYG65_RS01525 (331439)	331439..333118	-	1680	WP_000192007.1	cellulose biosynthesis protein BcsG	-
JYG65_RS01530 (333115)	333115..333306	-	192	WP_000981122.1	cellulose biosynthesis protein BcsF	-
JYG65_RS01535 (333303)	333303..334862	-	1560	WP_223666506.1	cellulose biosynthesis c-di-GMP-binding protein BcsE	-
JYG65_RS01540 (335149)	335149..335337	+	189	WP_001063310.1	cellulose biosynthesis protein BcsR	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3910.76 Da
• Isoelectric Point: 9.0157

>T194755 WP_223666505.1 NZ_CP070954:330764-330871 [Escherichia fergusonii]
MTLAELGMAFWHDLAAPVIVGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

>T194755 NZ_CP093965:c5351688-5351410 [Pseudomonas aeruginosa]
ATGATTCTGACCTTTCGCTGCGACGAGACTCGTCAGCTTTTTGAGACGGGTCTTTCGAGGCGGTGGGGAGCGATCCTCAC
AGTCGCTACGCGTAAGCTCGCAATGCTTCATGCGGCTACGGAGCTTCGAGACCTGCGCTCTCCACCTGGAAACCGGTTGG
AGCCGTTGCAGGGAAAGCGGGCGGGCCAACATAGCATCAGGATCAATGACCAGTGGCGTGTCTGTTTCGTCTGGACGGAT
GCGGGTCCCGAAGAAGTCGAAATAGTTGATTACCACTGA

Antitoxin

Nucleotide

• Length: 64 bp

>AT194755 NZ_CP070954:c330715-330652 [Escherichia fergusonii]
GTCTAGATGCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT

Structures

Antitoxin