Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1117579..1118089 Replicon chromosome
Accession NZ_CP070625
Organism Photobacterium damselae subsp. damselae strain RM-71

Toxin (Protein)


Gene name yoeB Uniprot ID A0A2T3QIJ8
Locus tag A0J47_RS19295 Protein ID WP_036765839.1
Coordinates 1117579..1117839 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A2T3QIT0
Locus tag A0J47_RS19300 Protein ID WP_036765838.1
Coordinates 1117829..1118089 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A0J47_RS19270 1113078..1113980 + 903 WP_068946067.1 LysR family transcriptional regulator -
A0J47_RS19275 1114042..1114878 - 837 WP_068946066.1 HNH endonuclease -
A0J47_RS19280 1115063..1116211 - 1149 WP_068946065.1 iron-containing alcohol dehydrogenase -
A0J47_RS19285 1116371..1117255 + 885 WP_068946064.1 AraC family transcriptional regulator -
A0J47_RS19290 1117267..1117521 + 255 WP_036765840.1 hypothetical protein -
A0J47_RS19295 1117579..1117839 - 261 WP_036765839.1 Txe/YoeB family addiction module toxin Toxin
A0J47_RS19300 1117829..1118089 - 261 WP_036765838.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
A0J47_RS19305 1118278..1119960 - 1683 WP_068946095.1 RluA family pseudouridine synthase -
A0J47_RS19310 1120035..1120769 - 735 WP_068946063.1 hypothetical protein -
A0J47_RS19315 1120776..1120994 - 219 WP_050787827.1 YgjV family protein -
A0J47_RS19320 1121170..1121787 - 618 WP_005305882.1 TPM domain-containing protein -
A0J47_RS19325 1121790..1122545 - 756 WP_068946062.1 TPM domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10319.86 Da        Isoelectric Point: 9.7118

>T194513 WP_036765839.1 NZ_CP070625:c1117839-1117579 [Photobacterium damselae subsp. damselae]
MMINFTPNAWDDYLYWQSQDKKTLKRINKLIENCVRTPFEGIGKPEPLKDNLSGYWSRRIDDTHRLVYKATQDTLVIVAV
RFHYQK

Download         Length: 261 bp

>T194513 NZ_CP093539:818350-818712 [Staphylococcus hominis]
ATGATTAGAAGAGGCGATGTATATTTAGCTGATTTATCACCAGTTCAAGGGTCTGAACAAGGGGGAGTAAGACCTGTAGT
TATCATTCAAAATGATACTGGTAATAAATATAGTCCTACAGTAATCGTTGCTGCGATTACTGGTAGGATTAATAAAGCGA
AAATACCAACACATGTAGAAATAGAAAAGAAAAAATATCGTTTAGATAAAGATTCAGTCATTCTTTTAGAACAAATACGA
ACATTGGATAAAAAAAGATTGAAAGAGAAACTTACATATTTATCAGAAGATAAAATGAAAGAAGTTGACGATGCATTGGA
TATCAGTTTAGGTTTACACGATGTTTGTCCTCAAAAAAATTAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9718.89 Da        Isoelectric Point: 4.3167

>AT194513 WP_036765838.1 NZ_CP070625:c1118089-1117829 [Photobacterium damselae subsp. damselae]
MTVLSFSEVRGNFKKVCDQVVDDCDAVVIHRRDADNVVLMSESEFNSWKETMYLMSNPVNAANLLESIKQAECGNVQTHE
LLSHDD

Download         Length: 261 bp

>AT194513 NZ_CP093539:818183-818353 [Staphylococcus hominis]
ATGTTAACTTTTAATCAGAATAGAAGCCATAGTCTTGAACAATCACTAAAAGAAGGCTATGTCCAAATGGCCGATTTAAA
CCTCTCCCTAGCAACTGAAGCATTTCCATTAGAATGTGAAGCTTGTGATTGTAACGAATCATATCTTACATCTAATTATA
AAAGTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2T3QIJ8

Antitoxin

Source ID Structure
AlphaFold DB A0A2T3QIT0

References