194507

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 997410..997966 Replicon plasmid unnamed1
Accession NZ_CP070610
Organism Rhodococcus koreensis strain R85

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag JWS14_RS45495 Protein ID WP_206016758.1
Coordinates 997706..997966 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag JWS14_RS45490 Protein ID WP_206016757.1
Coordinates 997410..997709 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JWS14_RS45440 992534..992754 + 221 Protein_883 hypothetical protein -
JWS14_RS45445 992770..993543 + 774 WP_005563657.1 3-oxoacyl-ACP reductase FabG -
JWS14_RS45450 993540..993995 + 456 WP_005563656.1 MaoC family dehydratase -
JWS14_RS45455 994607..995026 + 420 WP_206016754.1 MarR family transcriptional regulator -
JWS14_RS45460 995063..995518 + 456 WP_206016755.1 hypothetical protein -
JWS14_RS45465 995515..995781 + 267 WP_169695331.1 hypothetical protein -
JWS14_RS45470 995795..996108 + 314 Protein_889 rhodanese-like domain-containing protein -
JWS14_RS45475 996370..996540 + 171 WP_005563647.1 hypothetical protein -
JWS14_RS45480 996748..997188 + 441 WP_206016756.1 hypothetical protein -
JWS14_RS45485 997236..997427 - 192 WP_164065325.1 excalibur calcium-binding domain-containing protein -
JWS14_RS45490 997410..997709 + 300 WP_206016757.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
JWS14_RS45495 997706..997966 + 261 WP_206016758.1 Txe/YoeB family addiction module toxin Toxin
JWS14_RS45500 998610..1001585 + 2976 WP_206016759.1 UPF0182 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..1241328 1241328


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(18-89)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10454.89 Da        Isoelectric Point: 9.4090

>T194507 WP_206016758.1 NZ_CP070610:997706-997966 [Rhodococcus koreensis]
MKLVWDESAWEDYVWWQAQDRKIVKRIDTLLKDVERNGNDGIGKPEPLKHGFQGYWSRRITDEHRLVYKIVDHQIRIAAC
RYRYGH

Download         Length: 261 bp

>T194507 NZ_CP093535:439096-439509 [Ralstonia pseudosolanacearum]
ATGCCCGCGACTGAGGCATTCTTCGACAGCAATGTCGTGCTGTACCTGCTGTCGGCCGACACCGCCAAGGCCGATGCGGC
GGAAACGCTGCTGATGACCGGCGGTGTCGTCAGCGTACAGGTACTGAACGAAACGACGCACGTAATGCGCCGCAAGCTGG
CCATGCCGTGGCACGCGATCGAAACGGTGCAGGAGGCCGTGCGTGCGCAATGCCGGGTCGAGCCGCTGACGCTCGAAACC
CATGATCTCGGACGGCGTATCGCAGAACGCTACGGATTGTCGGTCTATGACGCACTGATCGTCGCGGCGGCATTGCTTGC
CGGCTGCAACGTTCTGTATTCCGAGGATATGCAGCACGGCCTGGTGATCGAGCAGCATCTGCGCATCGTCAATCCTTTTC
CGGCACGGGCATGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11059.48 Da        Isoelectric Point: 4.8838

>AT194507 WP_206016757.1 NZ_CP070610:997410-997709 [Rhodococcus koreensis]
MSGCVQFLVRNNGGVLRRTMTYSESRARYAEVLNAVVDDREEIVITRAGHEPVVMVSLDDYESLKETAYLLRSPENARRL
LASIDRLESGGGTVRDLAE

Download         Length: 300 bp

>AT194507 NZ_CP093535:438876-439109 [Ralstonia pseudosolanacearum]
ATGCAAGTCTCGAAATGGGGCAACAGCCTCGCTATCCGGCTGCCGGCGGCCGTTGTGGAGGCGCTTCAGCTGCACGAAGG
CGACGACGTCGAGGTGGTGATCGCGGGCGAGCGCTCGTTTGGCGTCCGCCGCAAGCGCGCTGCGCGCGAGCTTTTCGACC
GGATCCACCAATATCGCGGCAAGCTGCCCGCCGATTTCATCTTCGAGCGCGACCAGGCCAATGCCCGCGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References