Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
| Location | 4160584..4161236 | Replicon | chromosome |
| Accession | NZ_CP070508 | ||
| Organism | Serratia ureilytica strain AM923 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | A0A8E2QRT0 |
| Locus tag | IHE77_RS19920 | Protein ID | WP_033644839.1 |
| Coordinates | 4160584..4160928 (+) | Length | 115 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | IHE77_RS19925 | Protein ID | WP_025304078.1 |
| Coordinates | 4160934..4161236 (+) | Length | 101 a.a. |
Genomic Context
Location: 4159406..4160425 (1020 bp)
Type: Others
Protein ID: WP_033644840.1
Type: Others
Protein ID: WP_033644840.1
Location: 4160584..4160928 (345 bp)
Type: Toxin
Protein ID: WP_033644839.1
Type: Toxin
Protein ID: WP_033644839.1
Location: 4160934..4161236 (303 bp)
Type: Antitoxin
Protein ID: WP_025304078.1
Type: Antitoxin
Protein ID: WP_025304078.1
Location: 4162660..4163583 (924 bp)
Type: Others
Protein ID: WP_046687734.1
Type: Others
Protein ID: WP_046687734.1
Location: 4164628..4165512 (885 bp)
Type: Others
Protein ID: WP_069100465.1
Type: Others
Protein ID: WP_069100465.1
Location: 4165581..4166228 (648 bp)
Type: Others
Protein ID: WP_033644834.1
Type: Others
Protein ID: WP_033644834.1
Location: 4156927..4159185 (2259 bp)
Type: Others
Protein ID: WP_241439483.1
Type: Others
Protein ID: WP_241439483.1
Location: 4161264..4162526 (1263 bp)
Type: Others
Protein ID: WP_033644838.1
Type: Others
Protein ID: WP_033644838.1
Location: 4163611..4164519 (909 bp)
Type: Others
Protein ID: WP_033644836.1
Type: Others
Protein ID: WP_033644836.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IHE77_RS19910 (IHE77_19870) | 4156927..4159185 | - | 2259 | WP_241439483.1 | molybdopterin guanine dinucleotide-containing S/N-oxide reductase | - |
| IHE77_RS19915 (IHE77_19875) | 4159406..4160425 | + | 1020 | WP_033644840.1 | HTH-type transcriptional regulator GalR | - |
| IHE77_RS19920 (IHE77_19880) | 4160584..4160928 | + | 345 | WP_033644839.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| IHE77_RS19925 (IHE77_19885) | 4160934..4161236 | + | 303 | WP_025304078.1 | helix-turn-helix transcriptional regulator | Antitoxin |
| IHE77_RS19930 (IHE77_19890) | 4161264..4162526 | - | 1263 | WP_033644838.1 | diaminopimelate decarboxylase | - |
| IHE77_RS19935 (IHE77_19895) | 4162660..4163583 | + | 924 | WP_046687734.1 | LysR family transcriptional regulator | - |
| IHE77_RS19940 (IHE77_19900) | 4163611..4164519 | - | 909 | WP_033644836.1 | LysR family transcriptional regulator | - |
| IHE77_RS19945 (IHE77_19905) | 4164628..4165512 | + | 885 | WP_069100465.1 | MBL fold metallo-hydrolase | - |
| IHE77_RS19950 (IHE77_19910) | 4165581..4166228 | + | 648 | WP_033644834.1 | DsbA family protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 115 a.a. Molecular weight: 13339.39 Da Isoelectric Point: 10.8296
>T194237 WP_033644839.1 NZ_CP070508:4160584-4160928 [Serratia ureilytica]
MWQVVTVERFDDWFLALNNAQQTSILAAIFKLQTFGPQLARPHADTLHFSEAARQLKELRVQHRGRPFRVFFAFDPQRQA
VLLCGGDKTGDKRFYQRMLPIAAMEFSHYLATRR
MWQVVTVERFDDWFLALNNAQQTSILAAIFKLQTFGPQLARPHADTLHFSEAARQLKELRVQHRGRPFRVFFAFDPQRQA
VLLCGGDKTGDKRFYQRMLPIAAMEFSHYLATRR
Download Length: 345 bp
>T194237 NZ_CP093392:2064201-2064304 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 101 a.a. Molecular weight: 11081.01 Da Isoelectric Point: 10.3986
>AT194237 WP_025304078.1 NZ_CP070508:4160934-4161236 [Serratia ureilytica]
MAKPLSQLIDKLDPAVVAAARQKADKEIFELRLAMLREELAVSQVELAKRLGISQPSVANLEKRGSEIKLSSLKRYIEAM
GGTLSLDVQLPNGQHRRMTL
MAKPLSQLIDKLDPAVVAAARQKADKEIFELRLAMLREELAVSQVELAKRLGISQPSVANLEKRGSEIKLSSLKRYIEAM
GGTLSLDVQLPNGQHRRMTL
Download Length: 303 bp
>AT194237 NZ_CP093392:c2064306-2064163 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG