Detailed information of TA system TA194211

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 55436..56138
• Replicon: plasmid unnamed
• Accession: NZ_CP070504
• Organism: Pseudomonas atacamensis strain SM1

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: -
• Locus tag: JWU58_RS26990
• Protein ID: WP_206422289.1
• Coordinates: 55436..55735 (+)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: -
• Locus tag: JWU58_RS26995
• Protein ID: WP_206422290.1
• Coordinates: 55737..56138 (+)
• Length: 134 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JWU58_RS26960	50979..52784	+	1806	WP_206422283.1	DNA cytosine methyltransferase	-
JWU58_RS26965	52831..53268	+	438	WP_206422284.1	hypothetical protein	-
JWU58_RS26970	53258..54070	+	813	WP_206422285.1	hypothetical protein	-
JWU58_RS26975	54168..54305	+	138	WP_206422286.1	hypothetical protein	-
JWU58_RS26980	54390..55028	+	639	WP_206422287.1	hypothetical protein	-
JWU58_RS26985	55070..55282	+	213	WP_206422288.1	hypothetical protein	-
JWU58_RS26990	55436..55735	+	300	WP_206422289.1	type II toxin-antitoxin system MqsR family toxin	Toxin
JWU58_RS26995	55737..56138	+	402	WP_206422290.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
JWU58_RS27000	56135..56353	+	219	WP_206422291.1	hypothetical protein	-
JWU58_RS27005	56366..56551	+	186	WP_206422292.1	hypothetical protein	-
JWU58_RS27010	56558..56779	+	222	WP_206422293.1	hypothetical protein	-
JWU58_RS27015	56839..57138	+	300	WP_192096875.1	hypothetical protein	-
JWU58_RS27020	57232..57474	+	243	WP_206422294.1	hypothetical protein	-
JWU58_RS27025	57739..57885	-	147	WP_206422295.1	hypothetical protein	-
JWU58_RS27030	58011..58262	+	252	WP_206422296.1	hypothetical protein	-
JWU58_RS27035	59082..59819	+	738	WP_206422297.1	hypothetical protein	-
JWU58_RS27040	59816..60499	+	684	WP_206422298.1	hypothetical protein	-
JWU58_RS27045	60496..60900	+	405	WP_206422299.1	DUF2591 family protein	-
JWU58_RS27050	60897..61076	+	180	WP_206422300.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..81190	81190

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (2-98)

Antitoxin

• Cro/C1-type helix-turn-helix domain (74-111)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 10856.68 Da
• Isoelectric Point: 9.7498

>T194211 WP_206422289.1 NZ_CP070504:55436-55735 [Pseudomonas atacamensis]
MEKRTPHCKLSAVKALIGAGKVKSTTTALAGAAALGFDFEGMVGIVMLLKPADFYKSMTTYADHTTWQDVYRPKLGDGRR
VYLKLTVTDDALIVSFKEQ

Nucleotide

• Length: 300 bp

>T194211 NZ_CP093390:3439294-3439512 [Salmonella enterica]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin

Protein

• Length: 134 a.a.
• Molecular weight: 14304.59 Da
• Isoelectric Point: 7.6704

>AT194211 WP_206422290.1 NZ_CP070504:55737-56138 [Pseudomonas atacamensis]
MKCPICGGAELVTDTRDLPYTYKNESTVIPAVHGEFCSACGESILGVAESNRVSAAMLAFNKTVNAAVVDPLFITSVRKK
LALDQRQAAEIFGGGTNAFSRYETGKVKPPIALVLLLKLLDRHPELLNEVRAA

Nucleotide

• Length: 402 bp

>AT194211 NZ_CP093390:3438892-3439266 [Salmonella enterica]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGATTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTCCGTTGTTTCGTCAACGCCACCAGGGCCAATCCTGTTAGTTTGTCTTGTTAA