Detailed information of TA system TA193814

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-SprF1/-
• Location: 2786352..2786659
• Replicon: chromosome
• Accession: NZ_CP070305
• Organism: Staphylococcus sp. SM3655

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: JQN76_RS13760
• Protein ID: WP_072353918.1
• Coordinates: 2786483..2786659 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	2786352..2786491 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JQN76_RS13720	2781918..2782097	+	180	WP_000669789.1	hypothetical protein	-
JQN76_RS13725	2782408..2782668	+	261	WP_001791826.1	hypothetical protein	-
JQN76_RS13730	2782721..2783071	-	351	WP_000702262.1	complement inhibitor SCIN-A	-
JQN76_RS13735	2783581..2783916	-	336	Protein_2667	SH3 domain-containing protein	-
JQN76_RS13740	2784568..2785059	-	492	WP_000920041.1	staphylokinase	-
JQN76_RS13745	2785250..2786005	-	756	WP_000861038.1	CHAP domain-containing protein	-
JQN76_RS13750	2786017..2786271	-	255	WP_000611512.1	phage holin	-
JQN76_RS13755	2786323..2786430	+	108	WP_001791821.1	hypothetical protein	-
-	2786352..2786491	+	140	NuclAT_0	-	Antitoxin
-	2786352..2786491	+	140	NuclAT_0	-	Antitoxin
-	2786352..2786491	+	140	NuclAT_0	-	Antitoxin
-	2786352..2786491	+	140	NuclAT_0	-	Antitoxin
JQN76_RS13760	2786483..2786659	-	177	WP_072353918.1	putative holin-like toxin	Toxin
JQN76_RS13765	2786802..2787176	-	375	WP_000340977.1	hypothetical protein	-
JQN76_RS13770	2787232..2787519	-	288	WP_001262620.1	hypothetical protein	-
JQN76_RS13775	2787565..2787717	-	153	WP_001000058.1	hypothetical protein	-
JQN76_RS13780	2787710..2791492	-	3783	WP_001836550.1	phage protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (30-58)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6810.43 Da
• Isoelectric Point: 9.9479

>T193814 WP_072353918.1 NZ_CP070305:c2786659-2786483 [Staphylococcus sp. SM3655]
MDRWWLSEYKEVVPMLALLKSLERRCLMITISTMLQFGLFLIALIGLVIKLIELSNKK

Nucleotide

• Length: 177 bp

>T193814 NZ_CP093226:1864436-1864687 [Escherichia coli]
ATGCGTACAATTAGTTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin

Nucleotide

• Length: 140 bp

>AT193814 NZ_CP070305:2786352-2786491 [Staphylococcus sp. SM3655]
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTT

Structures

Antitoxin