Detailed information of TA system TA193809

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 1076042..1076226
• Replicon: chromosome
• Accession: NZ_CP070305
• Organism: Staphylococcus sp. SM3655

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: JQN76_RS05205
• Protein ID: WP_000482647.1
• Coordinates: 1076042..1076149 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	1076166..1076226 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JQN76_RS05180	1071414..1071887	+	474	WP_000456489.1	GyrI-like domain-containing protein	-
JQN76_RS05185	1072010..1073221	-	1212	WP_001192075.1	multidrug effflux MFS transporter	-
JQN76_RS05190	1073403..1074062	-	660	WP_000831298.1	membrane protein	-
JQN76_RS05195	1074122..1075264	-	1143	WP_001176863.1	glycerate kinase	-
JQN76_RS05200	1075522..1075908	+	387	WP_000779360.1	flippase GtxA	-
JQN76_RS05205	1076042..1076149	+	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1076166..1076226	-	61	-	-	Antitoxin
JQN76_RS05210	1076853..1078616	+	1764	WP_001064814.1	ABC transporter ATP-binding protein/permease	-
JQN76_RS05215	1078641..1080374	+	1734	WP_000486494.1	ABC transporter ATP-binding protein/permease	-
JQN76_RS05220	1080605..1080772	+	168	WP_001790576.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T193809 WP_000482647.1 NZ_CP070305:1076042-1076149 [Staphylococcus sp. SM3655]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T193809 NZ_CP093226:655571-655885 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA

Antitoxin

Nucleotide

• Length: 61 bp

>AT193809 NZ_CP070305:c1076226-1076166 [Staphylococcus sp. SM3655]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin