Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4572348..4573048 Replicon chromosome
Accession NZ_CP070304
Organism Glaciimonas sp. PAMC28666

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag JQN73_RS19580 Protein ID WP_205320609.1
Coordinates 4572752..4573048 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag JQN73_RS19575 Protein ID WP_205320608.1
Coordinates 4572348..4572749 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JQN73_RS19540 4567396..4567581 + 186 WP_205320602.1 hypothetical protein -
JQN73_RS19545 4567578..4568075 + 498 WP_205320603.1 glycoside hydrolase family protein -
JQN73_RS19550 4568072..4568593 + 522 WP_205320604.1 hypothetical protein -
JQN73_RS19555 4568780..4569566 + 787 Protein_3846 DNA adenine methylase -
JQN73_RS19560 4569811..4570824 + 1014 WP_205320605.1 nucleoid-associated protein -
JQN73_RS19565 4571115..4572005 + 891 WP_205320606.1 hypothetical protein -
JQN73_RS19570 4572092..4572325 - 234 WP_205320607.1 hypothetical protein -
JQN73_RS19575 4572348..4572749 - 402 WP_205320608.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
JQN73_RS19580 4572752..4573048 - 297 WP_205320609.1 type II toxin-antitoxin system MqsR family toxin Toxin
JQN73_RS19585 4573746..4574489 - 744 WP_205320610.1 SDR family oxidoreductase -
JQN73_RS19590 4574750..4574895 + 146 Protein_3853 DUF3297 family protein -
JQN73_RS19595 4575231..4575929 + 699 WP_205320611.1 FCD domain-containing protein -
JQN73_RS19600 4575958..4576755 + 798 WP_205320612.1 phytanoyl-CoA dioxygenase family protein -
JQN73_RS19605 4576838..4577635 + 798 WP_205320613.1 glucose 1-dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-127)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11243.11 Da        Isoelectric Point: 8.9460

>T193804 WP_205320609.1 NZ_CP070304:c4573048-4572752 [Glaciimonas sp. PAMC28666]
MEKRTAHCKLSVIKRMIEAGQVRTTKMAREGATGLGFDFDDMIAVIFKLTTADFYKSMTTHADHRIWQDVYRPTTRAGEV
YLKLTVIDDVLIVSFKEL

Download         Length: 297 bp

>T193804 NZ_CP093222:780302-780664 [Staphylococcus epidermidis]
ATGATTAGAAGAGGAGATGTTTATTTAGCGGATTTATCACCAGTTCAAGGGTCTGAACAAGGGGGAGTAAGACCTGTAGT
TATCATTCAAAATGATACTGGTAATAAATATAGTCCAACTGTAATTGTAGCTGCGATTACTGGTAGGATTAATAAAGCGA
AAATACCAACCCACGTAGAAATTGAAAAGAAAAAGTATAAATTAGACAAAGATTCAGTTATTCTTCTTGAACAAATTAGA
ACACTAGATAAAAAGCGTTTAAAAGAAAAATTAACATTTTTATCAGAGAGTAAAATGATAGAGGTTGATAATGCCTTAGA
TATTAGTTTGGGATTAAATAACTTTGATCATCATAAATCTTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14694.00 Da        Isoelectric Point: 7.1892

>AT193804 WP_205320608.1 NZ_CP070304:c4572749-4572348 [Glaciimonas sp. PAMC28666]
MKCPSCAAAGLFHDTRDLPYTYKGETTILPLVTGDFCPACDESVLGMDESRRTMQLMLAFNKQINASIVDPGFIADVRKK
LHLDQREAAEIFGGGVNAFSRYENGKTKPPLALVKLLRVLDRHPDLLAEVRAT

Download         Length: 402 bp

>AT193804 NZ_CP093222:780135-780305 [Staphylococcus epidermidis]
ATGTTATCTTTTAATCAAAATAGAAACCACAGTCTTGAACAATCTTTAAAAGAAGGTTATGCACAAATGGCCGATTTAAA
CCTCTCCCTAGCAACAGAAGCTTTCCCGATAGAGTGTGAAGCTTGTGATTGCAATGAATCACATTTAATATCTAATTCAA
AGAATGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References