Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | hok-sok/- |
| Location | 54420..54684 | Replicon | plasmid pESA136_3 |
| Accession | NZ_CP070299 | ||
| Organism | Escherichia albertii strain Sample 165 | ||
Toxin (Protein)
| Gene name | pndA | Uniprot ID | U9Y6M3 |
| Locus tag | JRC44_RS25540 | Protein ID | WP_001331364.1 |
| Coordinates | 54532..54684 (+) | Length | 51 a.a. |
Antitoxin (RNA)
| Gene name | pndB | ||
| Locus tag | - | ||
| Coordinates | 54420..54477 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JRC44_RS25525 (50758) | 50758..51828 | - | 1071 | WP_000151579.1 | IncI1-type conjugal transfer protein TrbB | - |
| JRC44_RS25530 (51847) | 51847..53055 | - | 1209 | WP_001383960.1 | IncI1-type conjugal transfer protein TrbA | - |
| JRC44_RS25535 (53273) | 53273..54226 | - | 954 | WP_021513958.1 | hypothetical protein | - |
| - (54420) | 54420..54477 | - | 58 | NuclAT_0 | - | Antitoxin |
| - (54420) | 54420..54477 | - | 58 | NuclAT_0 | - | Antitoxin |
| - (54420) | 54420..54477 | - | 58 | NuclAT_0 | - | Antitoxin |
| - (54420) | 54420..54477 | - | 58 | NuclAT_0 | - | Antitoxin |
| JRC44_RS25540 (54532) | 54532..54684 | + | 153 | WP_001331364.1 | Hok/Gef family protein | Toxin |
| JRC44_RS25545 (54756) | 54756..55007 | - | 252 | WP_001291964.1 | hypothetical protein | - |
| JRC44_RS26890 (55506) | 55506..55601 | + | 96 | WP_001303310.1 | DinQ-like type I toxin DqlB | - |
| JRC44_RS25550 (55666) | 55666..55842 | - | 177 | WP_001054901.1 | hypothetical protein | - |
| JRC44_RS25555 (56174) | 56174..56383 | + | 210 | WP_000062602.1 | HEAT repeat domain-containing protein | - |
| JRC44_RS25560 (56455) | 56455..57117 | - | 663 | WP_060527638.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| JRC44_RS25565 (57188) | 57188..59356 | - | 2169 | WP_000698368.1 | DotA/TraY family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Conjugative plasmid | - | - | 1..82787 | 82787 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 51 a.a. Molecular weight: 5775.13 Da Isoelectric Point: 8.7948
>T193795 WP_001331364.1 NZ_CP070299:54532-54684 [Escherichia albertii]
MPQRTFLMMLIVICVTILCFVWMVRDSLCGLRLQQGNTVLVATLAYEVKR
MPQRTFLMMLIVICVTILCFVWMVRDSLCGLRLQQGNTVLVATLAYEVKR
Download Length: 153 bp
>T193795 NZ_CP093221:3356160-3356447 [Escherichia coli]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA
Antitoxin
Download Length: 58 bp
>AT193795 NZ_CP070299:c54477-54420 [Escherichia albertii]
GCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
GCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
