Detailed information of TA system TA193725

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): symE-ohsC/SymE(toxin)
• Location: 3827702..3828114
• Replicon: chromosome
• Accession: NZ_CP070290
• Organism: Escherichia albertii strain Sample 167

Toxin (Protein)

• Gene name: symE
• Uniprot ID: -
• Locus tag: JRC41_RS18320
• Protein ID: WP_059225014.1
• Coordinates: 3827773..3828114 (+)
• Length: 114 a.a.

Antitoxin (RNA)

Gene name	ohsC
Locus tag	-
Coordinates	3827702..3827778 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JRC41_RS18310 (3824615)	3824615..3826204	+	1590	WP_059235085.1	type I restriction-modification system methyltransferase	-
JRC41_RS18315 (3826201)	3826201..3827544	+	1344	WP_059235087.1	restriction endonuclease subunit S	-
- (3827702)	3827702..3827778	-	77	NuclAT_8	-	Antitoxin
- (3827702)	3827702..3827778	-	77	NuclAT_8	-	Antitoxin
- (3827702)	3827702..3827778	-	77	NuclAT_8	-	Antitoxin
- (3827702)	3827702..3827778	-	77	NuclAT_8	-	Antitoxin
- (3827702)	3827702..3827778	-	77	NuclAT_9	-	Antitoxin
- (3827702)	3827702..3827778	-	77	NuclAT_9	-	Antitoxin
- (3827702)	3827702..3827778	-	77	NuclAT_9	-	Antitoxin
- (3827702)	3827702..3827778	-	77	NuclAT_9	-	Antitoxin
JRC41_RS18320 (3827773)	3827773..3828114	+	342	WP_059225014.1	endoribonuclease SymE	Toxin
JRC41_RS22390 (3828161)	3828161..3829327	-	1167	WP_077629336.1	DUF1524 domain-containing protein	-
JRC41_RS22395 (3829381)	3829381..3830257	-	877	Protein_3613	DUF262 domain-containing protein	-
JRC41_RS18330 (3830482)	3830482..3830655	+	174	Protein_3614	GntR family transcriptional regulator	-
JRC41_RS18335 (3830808)	3830808..3831740	-	933	WP_059242218.1	Rpn family recombination-promoting nuclease/putative transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (20-71)

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 12384.20 Da
• Isoelectric Point: 7.8219

>T193725 WP_059225014.1 NZ_CP070290:3827773-3828114 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTTQPPAAEESE
LMQSLRQVCKLSARKQKQVQEFIGVITGKQKVA

Nucleotide

• Length: 342 bp

>T193725 NZ_CP093185:878241-878603 [Staphylococcus epidermidis]
ATGATTAGAAGAGGAGATGTTTATTTAGCGGATTTATCACCAGTTCAAGGGTCTGAACAAGGGGGAGTAAGACCTGTAGT
TATCATTCAAAATGATACTGGTAATAAATATAGTCCAACTGTAATTGTAGCTGCGATTACTGGTAGGATTAATAAAGCGA
AAATACCAACCCACGTAGAAATTGAAAAGAAAAAGTATAAATTAGACAAAGATTCAGTTATTCTTCTTGAACAAATTAGA
ACACTAGATAAAAAGCGTTTAAAAGAAAAATTAACATTTTTATCAGAGAGTAAAATGATAGAGGTTGATAATGCCTTAGA
TATTAGTTTGGGATTAAATAACTTTGATCATCATAAATCTTAA

Antitoxin

Nucleotide

• Length: 77 bp

>AT193725 NZ_CP070290:c3827778-3827702 [Escherichia albertii]
AGTCATGATTACTATTCTCCATAAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Structures

Antitoxin