Detailed information of TA system TA193691

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 3945668..3945926
• Replicon: chromosome
• Accession: NZ_CP070287
• Organism: Escherichia albertii strain Sample 168

Toxin (Protein)

• Gene name: hokC
• Uniprot ID: -
• Locus tag: JRC45_RS19510
• Protein ID: WP_001519334.1
• Coordinates: 3945774..3945926 (+)
• Length: 51 a.a.

Antitoxin (RNA)

Gene name	sokC
Locus tag	-
Coordinates	3945668..3945725 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JRC45_RS19495	3941475..3942723	-	1249	Protein_3861	cytoplasmic protein	-
JRC45_RS19500	3942877..3944370	-	1494	WP_204628790.1	sulfatase-like hydrolase/transferase	-
JRC45_RS19505	3944391..3945152	-	762	WP_208625529.1	outer membrane protein OmpK	-
-	3945668..3945725	-	58	-	-	Antitoxin
JRC45_RS19510	3945774..3945926	+	153	WP_001519334.1	type I toxin-antitoxin system toxin MokC	Toxin
JRC45_RS19515	3946030..3947160	-	1131	WP_001118445.1	molecular chaperone DnaJ	-
JRC45_RS19520	3947249..3949165	-	1917	WP_000516137.1	molecular chaperone DnaK	-
JRC45_RS19525	3949540..3949944	+	405	WP_000833521.1	DUF2541 family protein	-
JRC45_RS19530	3949971..3950684	+	714	WP_204628791.1	acidic protein MsyB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (6-47)

Sequences

Toxin

Protein

• Length: 51 a.a.
• Molecular weight: 5515.59 Da
• Isoelectric Point: 7.1312

>T193691 WP_001519334.1 NZ_CP070287:3945774-3945926 [Escherichia albertii]
MKQHKAMIIALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Nucleotide

• Length: 153 bp

>T193691 NZ_CP093154:1739839-1740192 [Enterobacter asburiae]
GTGTCGGCAATTAACACGACGGACAGGTTTGATCGCTGGTTTACTTCGCTTGACGATACCGAACGCGCCAGCGTACTTGC
AGCCCTGCTTGTTTTGCGAGAGAAGGGGCCGGGTTTATCGAGACCCTACGCCGATACGCTTAAAGGCTCTCGTCACAGCA
ACATGAAAGAGCTACGTATTCAGAGTAAGGGCGATCCCTTGCGGGCGTTTTTCGCCTTTGATCCAAACCGCACGGGTATC
GTGCTTTGTGCGGGCAATAAGGTCGGCAATGAAAGGCGATTCTACGATGAGATGCTTCTCGTTGCTGACCGGGAATTCAC
TCACTGGCTGAATACATTAAAAGAGAGGGAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT193691 NZ_CP070287:c3945725-3945668 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Structures

Antitoxin