Detailed information of TA system TA193620

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 3912463..3912721
• Replicon: chromosome
• Accession: NZ_CP070281
• Organism: Escherichia albertii strain Sample 170

Toxin (Protein)

• Gene name: hokC
• Uniprot ID: S1NX00
• Locus tag: JRC42_RS19230
• Protein ID: WP_000809168.1
• Coordinates: 3912569..3912721 (+)
• Length: 51 a.a.

Antitoxin (RNA)

Gene name	sokA
Locus tag	-
Coordinates	3912463..3912520 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JRC42_RS19215	3908271..3909518	-	1248	WP_059227922.1	hypothetical protein	-
JRC42_RS19220	3909672..3911165	-	1494	WP_059214855.1	sulfatase-like hydrolase/transferase	-
JRC42_RS19225	3911186..3911947	-	762	WP_204619628.1	outer membrane protein OmpK	-
-	3912463..3912520	-	58	-	-	Antitoxin
JRC42_RS19230	3912569..3912721	+	153	WP_000809168.1	type I toxin-antitoxin system toxin MokC	Toxin
JRC42_RS19235	3912825..3913955	-	1131	WP_204619629.1	molecular chaperone DnaJ	-
JRC42_RS19240	3914044..3915960	-	1917	WP_000516135.1	molecular chaperone DnaK	-
JRC42_RS19245	3916335..3916739	+	405	WP_000833521.1	DUF2541 family protein	-
JRC42_RS19250	3916766..3917479	+	714	WP_001102345.1	acidic protein MsyB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (6-47)

Sequences

Toxin

Protein

• Length: 51 a.a.
• Molecular weight: 5501.57 Da
• Isoelectric Point: 7.1312

>T193620 WP_000809168.1 NZ_CP070281:3912569-3912721 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Nucleotide

• Length: 153 bp

>T193620 NZ_CP093041:258751-259074 [Bartonella krasnovii]
ATGCGGGGTTCTCTTGTAACAATAGCTATGCAAGGTGATTTTGGTAAACCAAGACCTGCGTTAATCATTCAAGCTAATCA
ATTCAGTGAACATACAAGCGTGACGGTTTTACCCATTACAAGTACACTTATTGATGCTCCATTACTCCGCATTACGATTC
AGCCAAATGACAAGAATGGTTTGCAGAAACCTTCGCAAGTCATGATTGATAAAATTATGACGGTAAGATGTGAAAAAATT
AGTCCAGCTTTCGGTTTCATTCCTGTAGATAAAATGGTAGAAATTGAACGTTGTTTGGCTGTATTTTTAGGAATAGTAAA
ATAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT193620 NZ_CP070281:c3912520-3912463 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Structures

Toxin

• AlphaFold DB: S1NX00

Antitoxin