Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | ralRA/- |
| Location | 1023486..1023857 | Replicon | chromosome |
| Accession | NZ_CP070071 | ||
| Organism | Escherichia coli strain FDAARGOS_1287 | ||
Toxin (Protein)
| Gene name | ralR | Uniprot ID | A0A891STD1 |
| Locus tag | I6K17_RS05685 | Protein ID | WP_042853000.1 |
| Coordinates | 1023663..1023857 (-) | Length | 65 a.a. |
Antitoxin (RNA)
| Gene name | ralA | ||
| Locus tag | - | ||
| Coordinates | 1023486..1023664 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6K17_RS05645 (1018931) | 1018931..1019587 | - | 657 | WP_000011673.1 | carbon-nitrogen hydrolase family protein YobB | - |
| I6K17_RS05650 (1019689) | 1019689..1019919 | - | 231 | WP_000916759.1 | DNA polymerase III subunit theta | - |
| I6K17_RS05655 (1020058) | 1020058..1020432 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| I6K17_RS05660 (1020436) | 1020436..1021296 | + | 861 | Protein_992 | copper homeostasis membrane protein CopD | - |
| I6K17_RS05665 (1021319) | 1021319..1021660 | + | 342 | WP_000976472.1 | YebY family protein | - |
| I6K17_RS05670 (1022052) | 1022052..1023128 | - | 1077 | WP_204608769.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| I6K17_RS05675 (1023094) | 1023094..1023375 | - | 282 | WP_001311878.1 | excisionase | - |
| - (1023486) | 1023486..1023664 | + | 179 | NuclAT_0 | - | Antitoxin |
| - (1023486) | 1023486..1023664 | + | 179 | NuclAT_0 | - | Antitoxin |
| - (1023486) | 1023486..1023664 | + | 179 | NuclAT_0 | - | Antitoxin |
| - (1023486) | 1023486..1023664 | + | 179 | NuclAT_0 | - | Antitoxin |
| I6K17_RS05680 (1023482) | 1023482..1023670 | - | 189 | WP_204608772.1 | DUF1187 family protein | - |
| I6K17_RS05685 (1023663) | 1023663..1023857 | - | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | Toxin |
| I6K17_RS05690 (1023914) | 1023914..1024723 | - | 810 | WP_000166317.1 | recombination protein RecT | - |
| I6K17_RS05695 (1024716) | 1024716..1027391 | - | 2676 | WP_204608786.1 | exodeoxyribonuclease VIII | - |
| I6K17_RS05700 (1027491) | 1027491..1027766 | - | 276 | WP_001452559.1 | hypothetical protein | - |
| I6K17_RS05705 (1027841) | 1027841..1028011 | - | 171 | WP_001359121.1 | YdaE family protein | - |
| I6K17_RS05710 (1028011) | 1028011..1028232 | - | 222 | WP_000560227.1 | cell division protein FtsZ | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1016188..1081641 | 65453 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 65 a.a. Molecular weight: 7019.87 Da Isoelectric Point: 8.6419
>T192940 WP_042853000.1 NZ_CP070071:c1023857-1023663 [Escherichia coli]
MRYDDVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV
MRYDDVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV
Download Length: 195 bp
>T192940 NZ_CP092629:c6230848-6229979 [Pseudomonas aeruginosa]
ATGAACATGGCGCAGACCCACACCCCCGTCCCGAACCTGCAACAGCGCTTTCCCGAGCGGCTGGTGCAACTGGCCGACGG
CGCCCAGCTGGCCATCCGCGAATGCGGCCAGGGCCCGGTGGTGGTGCTGTTGCACGGCATCGGTTCGGGCTCGGCGTCCT
GGCTGCATTGCGCCCAGCGCCTGGCCGCCGGCAATCGGGTGATCGCCTGGGACGCGCCGGGTTACGGCCTGTCCACGCCG
CTGCCGCCGGCCCGGCCCAAGGCCTGCGACTACGCCGCGTGCCTGGAGCTGCTGCTGGATGCGCTGGGCGTGGAGAGCTG
CCTGCTGGTGGGCCACTCCCTCGGCGCGCTGATGGCCACGGCCTACGCCGCCGGCATCGGCGCGGCGCGGGTGCGCCGCC
TGGTGCTGCTCAGCCCGGCGCGCGGCTACGGCGCCGCCGAGCTGCGCGACAGCGGCGCCCAGGTGCGCCGCCAGCGCCTG
GAGAACCTGGAGCGCTTCGGTATCGACGGCATGGCCAGCGAGCGCACCGCGCGCCTGCTCGGCCGCAACCCCAGCGAGGA
GGCCCTGGCCTGGGTGCGCTGGAACATGGCGCGGCTCAACCCCGAGGGCTACCGCCAGGCCGTCGAGCTGCTCTGCGGCG
ACGACCTGCTGGGCAACGGGCAGCCTGCCGCTCCTTGCGAGGTGCATTGCGGCGAGGACGACGGCATCACCACGCCCGAG
AGTTGCGGCGCCATCGCCCGCCAGCTCGGCGCGTCGTTCTCGTCGATTCCCGGGGCCGGCCACGCCAGCCCGATCGAACA
ACCCGAAGTGGTCGCAGGACGCATCGGCCACGCGCAACGCCTCTCTCTTGAAGGAACCGCCAATGGATAA
ATGAACATGGCGCAGACCCACACCCCCGTCCCGAACCTGCAACAGCGCTTTCCCGAGCGGCTGGTGCAACTGGCCGACGG
CGCCCAGCTGGCCATCCGCGAATGCGGCCAGGGCCCGGTGGTGGTGCTGTTGCACGGCATCGGTTCGGGCTCGGCGTCCT
GGCTGCATTGCGCCCAGCGCCTGGCCGCCGGCAATCGGGTGATCGCCTGGGACGCGCCGGGTTACGGCCTGTCCACGCCG
CTGCCGCCGGCCCGGCCCAAGGCCTGCGACTACGCCGCGTGCCTGGAGCTGCTGCTGGATGCGCTGGGCGTGGAGAGCTG
CCTGCTGGTGGGCCACTCCCTCGGCGCGCTGATGGCCACGGCCTACGCCGCCGGCATCGGCGCGGCGCGGGTGCGCCGCC
TGGTGCTGCTCAGCCCGGCGCGCGGCTACGGCGCCGCCGAGCTGCGCGACAGCGGCGCCCAGGTGCGCCGCCAGCGCCTG
GAGAACCTGGAGCGCTTCGGTATCGACGGCATGGCCAGCGAGCGCACCGCGCGCCTGCTCGGCCGCAACCCCAGCGAGGA
GGCCCTGGCCTGGGTGCGCTGGAACATGGCGCGGCTCAACCCCGAGGGCTACCGCCAGGCCGTCGAGCTGCTCTGCGGCG
ACGACCTGCTGGGCAACGGGCAGCCTGCCGCTCCTTGCGAGGTGCATTGCGGCGAGGACGACGGCATCACCACGCCCGAG
AGTTGCGGCGCCATCGCCCGCCAGCTCGGCGCGTCGTTCTCGTCGATTCCCGGGGCCGGCCACGCCAGCCCGATCGAACA
ACCCGAAGTGGTCGCAGGACGCATCGGCCACGCGCAACGCCTCTCTCTTGAAGGAACCGCCAATGGATAA
Antitoxin
Download Length: 179 bp
>AT192940 NZ_CP070071:1023486-1023664 [Escherichia coli]
GAGGACAGAAGTTTCTCGCAATTAAAATTTATCAGCTTTACTTTCTGCTCTCTGGACACGCCTGCTTCTTTTTTCCCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAATTTAGATTTTGAATATCTTGTCCATTTAGTAGGAGTTCCACCTTCTTTTT
CAATAGTGGTAGTTATTTT
GAGGACAGAAGTTTCTCGCAATTAAAATTTATCAGCTTTACTTTCTGCTCTCTGGACACGCCTGCTTCTTTTTTCCCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAATTTAGATTTTGAATATCTTGTCCATTTAGTAGGAGTTCCACCTTCTTTTT
CAATAGTGGTAGTTATTTT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
