Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | sprA1-sprA1AS/- |
Location | 656..817 | Replicon | plasmid unnamed1 |
Accession | NZ_CP070059 | ||
Organism | Staphylococcus epidermidis strain FDAARGOS_1361 |
Toxin (Protein)
Gene name | sprA1 | Uniprot ID | - |
Locus tag | I6K91_RS11610 | Protein ID | WP_002441941.1 |
Coordinates | 656..751 (+) | Length | 32 a.a. |
Antitoxin (RNA)
Gene name | sprA1AS | ||
Locus tag | - | ||
Coordinates | 780..817 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
I6K91_RS11610 | 656..751 | + | 96 | WP_002441941.1 | type I toxin-antitoxin system Fst family toxin | Toxin |
- | 780..817 | - | 38 | NuclAT_0 | - | Antitoxin |
I6K91_RS11615 | 930..1703 | + | 774 | WP_204973963.1 | hypothetical protein | - |
I6K91_RS11620 | 1738..2739 | + | 1002 | WP_204973965.1 | nucleotidyltransferase | - |
I6K91_RS11625 | 2899..3507 | + | 609 | WP_103463550.1 | recombinase family protein | - |
I6K91_RS11630 | 3747..4799 | - | 1053 | WP_103463551.1 | bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase | - |
I6K91_RS11635 | 4802..5509 | - | 708 | WP_204973967.1 | thioesterase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..28412 | 28412 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 32 a.a. Molecular weight: 3560.34 Da Isoelectric Point: 9.9256
>T192863 WP_002441941.1 NZ_CP070059:656-751 [Staphylococcus epidermidis]
MLMIFVHIIAPVISGCAVAYFTYWLSSKRNK
MLMIFVHIIAPVISGCAVAYFTYWLSSKRNK
Download Length: 96 bp
>T192863 NZ_CP092567:c848530-848339 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAAT
GAAAAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATAT
TAATATACACATTTATATTTGGTGTGCTATAA
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAAT
GAAAAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATAT
TAATATACACATTTATATTTGGTGTGCTATAA
Antitoxin
Download Length: 38 bp
>AT192863 NZ_CP070059:c817-780 [Staphylococcus epidermidis]
TATGCACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
TATGCACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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