Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | ldrD-rdlD/Ldr(toxin) |
Location | 4247533..4247754 | Replicon | chromosome |
Accession | NZ_CP069980 | ||
Organism | Escherichia coli strain FDAARGOS_1291 |
Toxin (Protein)
Gene name | ldrD | Uniprot ID | B7LGX8 |
Locus tag | I6K21_RS20175 | Protein ID | WP_000170965.1 |
Coordinates | 4247533..4247640 (-) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | rdlD | ||
Locus tag | - | ||
Coordinates | 4247688..4247754 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
I6K21_RS20150 (4243378) | 4243378..4244460 | + | 1083 | WP_000804726.1 | peptide chain release factor 1 | - |
I6K21_RS20155 (4244460) | 4244460..4245293 | + | 834 | WP_000456458.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
I6K21_RS20160 (4245290) | 4245290..4245682 | + | 393 | WP_000151883.1 | invasion regulator SirB2 | - |
I6K21_RS20165 (4245686) | 4245686..4246495 | + | 810 | WP_001257044.1 | invasion regulator SirB1 | - |
I6K21_RS20170 (4246531) | 4246531..4247385 | + | 855 | WP_000811065.1 | 3-deoxy-8-phosphooctulonate synthase | - |
I6K21_RS20175 (4247533) | 4247533..4247640 | - | 108 | WP_000170965.1 | type I toxin-antitoxin system toxin Ldr family protein | Toxin |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_29 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_29 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_29 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_29 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_31 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_31 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_31 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_31 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_33 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_33 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_33 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_33 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_35 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_35 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_35 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_35 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_37 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_37 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_37 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_37 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_39 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_39 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_39 | - | - |
- (4247690) | 4247690..4247753 | + | 64 | NuclAT_39 | - | - |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_16 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_16 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_16 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_16 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_18 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_18 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_18 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_18 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_20 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_20 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_20 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_20 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_22 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_22 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_22 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_22 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_24 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_24 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_24 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_24 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_26 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_26 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_26 | - | Antitoxin |
- (4247688) | 4247688..4247754 | + | 67 | NuclAT_26 | - | Antitoxin |
- (4247690) | 4247690..4247755 | + | 66 | NuclAT_41 | - | - |
- (4247690) | 4247690..4247755 | + | 66 | NuclAT_41 | - | - |
- (4247690) | 4247690..4247755 | + | 66 | NuclAT_41 | - | - |
- (4247690) | 4247690..4247755 | + | 66 | NuclAT_41 | - | - |
I6K21_RS20180 (4248068) | 4248068..4248175 | - | 108 | WP_000170955.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_28 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_28 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_28 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_28 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_30 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_30 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_30 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_30 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_32 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_32 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_32 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_32 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_34 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_34 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_34 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_34 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_36 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_36 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_36 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_36 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_38 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_38 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_38 | - | - |
- (4248228) | 4248228..4248289 | + | 62 | NuclAT_38 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_17 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_17 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_17 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_17 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_19 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_19 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_19 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_19 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_21 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_21 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_21 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_21 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_23 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_23 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_23 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_23 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_25 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_25 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_25 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_25 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_27 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_27 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_27 | - | - |
- (4248228) | 4248228..4248290 | + | 63 | NuclAT_27 | - | - |
- (4248228) | 4248228..4248291 | + | 64 | NuclAT_40 | - | - |
- (4248228) | 4248228..4248291 | + | 64 | NuclAT_40 | - | - |
- (4248228) | 4248228..4248291 | + | 64 | NuclAT_40 | - | - |
- (4248228) | 4248228..4248291 | + | 64 | NuclAT_40 | - | - |
I6K21_RS20185 (4248581) | 4248581..4249681 | - | 1101 | WP_001309461.1 | sodium-potassium/proton antiporter ChaA | - |
I6K21_RS20190 (4249951) | 4249951..4250181 | + | 231 | WP_001146444.1 | putative cation transport regulator ChaB | - |
I6K21_RS20195 (4250339) | 4250339..4251034 | + | 696 | WP_001295621.1 | glutathione-specific gamma-glutamylcyclotransferase | - |
I6K21_RS20200 (4251078) | 4251078..4251431 | - | 354 | WP_001169659.1 | DsrE/F sulfur relay family protein YchN | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 4001.77 Da Isoelectric Point: 11.4779
>T192480 WP_000170965.1 NZ_CP069980:c4247640-4247533 [Escherichia coli]
MTLAQFAMTFWHDLAAPILAGIITAAIVSWWRNRK
MTLAQFAMTFWHDLAAPILAGIITAAIVSWWRNRK
Download Length: 108 bp
>T192480 NZ_CP069980:c4247640-4247533 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 67 bp
>AT192480 NZ_CP069980:4247688-4247754 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTATACCTCTCAACGTGCGGGGGTTTTCTC
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTATACCTCTCAACGTGCGGGGGTTTTCTC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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