Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3505738..3505960 Replicon chromosome
Accession NZ_CP069935
Organism Escherichia coli strain FDAARGOS_1302

Toxin (Protein)


Gene name ldrD Uniprot ID A0A0D6GD35
Locus tag I6K32_RS17100 Protein ID WP_000170745.1
Coordinates 3505738..3505845 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3505902..3505960 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K32_RS17070 3500791..3500979 - 189 WP_001063314.1 cellulose biosynthesis protein BcsR -
I6K32_RS17075 3501252..3502823 + 1572 WP_001204957.1 cellulose biosynthesis c-di-GMP-binding protein BcsE -
I6K32_RS17080 3502820..3503011 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
I6K32_RS17085 3503008..3504687 + 1680 WP_000191567.1 cellulose biosynthesis protein BcsG -
I6K32_RS17090 3504773..3504880 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
I6K32_RS17095 3505256..3505363 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
I6K32_RS17100 3505738..3505845 - 108 WP_000170745.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- 3505902..3505960 + 59 - - Antitoxin
I6K32_RS17105 3506321..3507592 + 1272 WP_001332306.1 aromatic amino acid transport family protein -
I6K32_RS17110 3507622..3508626 - 1005 WP_000103579.1 dipeptide ABC transporter ATP-binding subunit DppF -
I6K32_RS17115 3508623..3509606 - 984 WP_001196477.1 dipeptide ABC transporter ATP-binding protein -
I6K32_RS17120 3509617..3510519 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3855.68 Da        Isoelectric Point: 9.0157

>T192156 WP_000170745.1 NZ_CP069935:c3505845-3505738 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVSWLNKRK

Download         Length: 108 bp

>T192156 NZ_CP092106:1749664-1749936 [Vibrio sp. JC009]
ATGTACGCTCTTGAGTATTCCACTCAGTTTAAGAAAGACTTCAAGAAGGTAACTAAAAAGCCTATTTCTGACATCATGGA
AGTTGGATATGTAGTATCAAAACTGCAGAGAGGTGAAACACTTGAAGAGAAGTTTGTAGATCATCCATTAACAAGTAATT
GGGCTGGTTTCAGGGATTGTCACGTAAAACCTGACTTAGTATTAATCTATAGAATAGAACACAGCACACTACAACTAGCC
CGGATAGGCACACATAGTGAATTATTTGGGTAA

Antitoxin


Download         Length: 59 bp

>AT192156 NZ_CP069935:3505902-3505960 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D6GD35

Antitoxin

Download structure file

References