Detailed information of TA system TA190993

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 18065..18213
• Replicon: plasmid unnamed
• Accession: NZ_CP069581
• Organism: Staphylococcus carnosus strain FDAARGOS_1204

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: I6J34_RS00080
• Protein ID: WP_011276848.1
• Coordinates: 18118..18213 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	18065..18100 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6J34_RS00065	13100..14875	-	1776	WP_115359487.1	oleate hydratase	-
I6J34_RS00070	15244..15852	-	609	WP_046100649.1	recombinase family protein	-
I6J34_RS00075	16100..17858	+	1759	Protein_14	retron Ec67 family RNA-directed DNA polymerase/endonuclease	-
-	18065..18100	-	36	NuclAT_0	-	Antitoxin
I6J34_RS00080	18118..18213	-	96	WP_011276848.1	type I toxin-antitoxin system Fst family toxin	Toxin
I6J34_RS00085	18540..19082	-	543	WP_082080603.1	peptide deformylase	-
I6J34_RS00090	19102..19299	-	198	WP_039069675.1	helix-turn-helix transcriptional regulator	-
I6J34_RS00095	19604..20032	-	429	WP_103211967.1	Hsp20/alpha crystallin family protein	-
I6J34_RS00100	20054..20224	-	171	WP_160149154.1	hypothetical protein	-
I6J34_RS00105	20935..21141	-	207	Protein_20	protein rep	-
I6J34_RS00110	21147..22148	-	1002	WP_103211966.1	replication initiator protein A	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..33442	33442

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3623.38 Da
• Isoelectric Point: 9.5124

>T190993 WP_011276848.1 NZ_CP069581:c18213-18118 [Staphylococcus carnosus]
MLEILVHITTTVISGCIIALFTHWLRNRKDK

Nucleotide

• Length: 96 bp

>T190993 NZ_CP091607:c4496242-4495931 [Salmonella enterica]
ATGCAATTTATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGATGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGAGCGCGAG
GCAAAGGAAAGCGTAGTGGCGTGCGAATTATCTATTTTCACCGTAGTCAACGGTATGAGATTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGCTGAATGAGAGGTGGTAG

Antitoxin

Nucleotide

• Length: 36 bp

>AT190993 NZ_CP069581:c18100-18065 [Staphylococcus carnosus]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin