Detailed information of TA system TA190897

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 587334..587556
• Replicon: chromosome
• Accession: NZ_CP069559
• Organism: Escherichia coli strain FDAARGOS_1259

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: A0A0D6GD35
• Locus tag: I6J89_RS02760
• Protein ID: WP_000170745.1
• Coordinates: 587449..587556 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	587334..587392 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6J89_RS02740	582775..583677	+	903	WP_000084677.1	dipeptide ABC transporter permease DppC	-
I6J89_RS02745	583688..584671	+	984	WP_001196477.1	dipeptide ABC transporter ATP-binding protein	-
I6J89_RS02750	584668..585672	+	1005	WP_000103583.1	dipeptide ABC transporter ATP-binding subunit DppF	-
I6J89_RS02755	585702..586973	-	1272	WP_001467807.1	amino acid permease	-
-	587334..587392	-	59	-	-	Antitoxin
I6J89_RS02760	587449..587556	+	108	WP_000170745.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
I6J89_RS02765	587643..589322	-	1680	WP_000191567.1	cellulose biosynthesis protein BcsG	-
I6J89_RS02770	589319..589510	-	192	WP_000988311.1	cellulose biosynthesis protein BcsF	-
I6J89_RS02775	589507..591078	-	1572	WP_001204945.1	cellulose biosynthesis protein BcsE	-
I6J89_RS02780	591351..591539	+	189	WP_001063314.1	YhjR family protein	-
I6J89_RS02785	591551..592303	+	753	WP_000279525.1	cellulose biosynthesis protein BcsQ	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3855.68 Da
• Isoelectric Point: 9.0157

>T190897 WP_000170745.1 NZ_CP069559:587449-587556 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVSWLNKRK

Nucleotide

• Length: 108 bp

>T190897 NZ_CP091569:2107777-2107880 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin

Nucleotide

• Length: 59 bp

>AT190897 NZ_CP069559:c587392-587334 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A0D6GD35

Antitoxin