Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4190889..4191147 Replicon chromosome
Accession NZ_CP069522
Organism Escherichia coli strain FDAARGOS_1267

Toxin (Protein)


Gene name hokC Uniprot ID -
Locus tag I6J97_RS20185 Protein ID WP_001519334.1
Coordinates 4190995..4191147 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 4190889..4190946 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6J97_RS20170 4186718..4187977 - 1260 WP_000494929.1 hypothetical protein -
I6J97_RS20175 4188106..4189599 - 1494 Protein_3956 sulfatase-like hydrolase/transferase -
I6J97_RS20180 4189619..4190380 - 762 WP_001274832.1 hypothetical protein -
- 4190889..4190946 - 58 - - Antitoxin
I6J97_RS20185 4190995..4191147 + 153 WP_001519334.1 type I toxin-antitoxin system toxin MokC Toxin
I6J97_RS20190 4191252..4192382 - 1131 WP_001118464.1 molecular chaperone DnaJ -
I6J97_RS20195 4192471..4194387 - 1917 WP_000516135.1 molecular chaperone DnaK -
I6J97_RS20200 4194759..4195163 + 405 WP_000843692.1 DUF2541 family protein -
I6J97_RS20205 4195189..4195902 + 714 WP_001102393.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5515.59 Da        Isoelectric Point: 7.1312

>T190780 WP_001519334.1 NZ_CP069522:4190995-4191147 [Escherichia coli]
MKQHKAMIIALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

>T190780 NZ_CP069522:4190995-4191147 [Escherichia coli]
ATGAAGCAGCATAAGGCGATGATTATCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA

Antitoxin


Download         Length: 58 bp

>AT190780 NZ_CP069522:c4190946-4190889 [Escherichia coli]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References