Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1367917..1368707 Replicon chromosome
Accession NZ_CP069352
Organism Pseudomonas granadensis isolate CT364

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag JN757_RS05915 Protein ID WP_203420838.1
Coordinates 1368396..1368707 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag JN757_RS05910 Protein ID WP_093104526.1
Coordinates 1367917..1368399 (-) Length 161 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN757_RS05890 1363702..1364733 + 1032 WP_090281876.1 amino acid ABC transporter substrate-binding protein -
JN757_RS05895 1364800..1365981 + 1182 WP_203420837.1 amino acid ABC transporter permease -
JN757_RS05900 1365992..1367086 + 1095 WP_090281878.1 amino acid ABC transporter permease -
JN757_RS05905 1367100..1367864 + 765 WP_090281879.1 amino acid ABC transporter ATP-binding protein -
JN757_RS05910 1367917..1368399 - 483 WP_093104526.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
JN757_RS05915 1368396..1368707 - 312 WP_203420838.1 type II toxin-antitoxin system MqsR family toxin Toxin
JN757_RS05920 1368874..1369533 + 660 WP_203420839.1 FadR family transcriptional regulator -
JN757_RS05925 1369523..1370827 + 1305 WP_203420840.1 CynX/NimT family MFS transporter -
JN757_RS05930 1371033..1371503 + 471 WP_203420841.1 nuclear transport factor 2 family protein -
JN757_RS05935 1371544..1371846 + 303 WP_203420842.1 GIY-YIG nuclease family protein -
JN757_RS05940 1371931..1372866 + 936 WP_203420843.1 glutathione S-transferase family protein -
JN757_RS05945 1372986..1373336 - 351 WP_203420844.1 glutaredoxin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-100)

Antitoxin

Antitoxin MqsA

(6-133)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12316.00 Da        Isoelectric Point: 9.5902

>T190246 WP_203420838.1 NZ_CP069352:c1368707-1368396 [Pseudomonas granadensis]
MEKNTPHYDLAVIKADVRRLGWRAFTHTARRSGSELELTLADMQEVVFRLQRSMLYKSMTTYDNHRIWQDVYHINSHGLE
IYIKVSYHYDKRPPVISFKENNS

Download         Length: 312 bp

>T190246 NZ_CP091198:1173871-1173975 [Enterococcus faecalis]
TTGTCAGCATATGAAACAATTCAGACAATTCTTGGGTTTGGTATGTTTACCATTGCTTTGATTGCGCTGATTGTGAAATT
GCTTAAAAATGACAAGAAAAAATAA

Antitoxin


Download         Length: 161 a.a.        Molecular weight: 18060.66 Da        Isoelectric Point: 6.7367

>AT190246 WP_093104526.1 NZ_CP069352:c1368399-1367917 [Pseudomonas granadensis]
MSTQQCFSCGAAEGMVHFDGRGETVSVKGMERRIDNLSGWECQKCGEVELDEMCGQRYSDACDELVIASRKMVGNEMRRI
RRKLHLTQKETVQLLSGGGHNAFSRYERGEILPPKALILLMRLLDRYPYLLTDAKTLGEGADLRGFEHIVHKEHESLSVS

Download         Length: 483 bp

>AT190246 NZ_CP091198:c1174163-1173908 [Enterococcus faecalis]
ATAAAAATGCCCGAGCCTTGAAATAGGAGGCTCAGGCATTTTTTATTGATGGTCTTTTTAGGGTTGTTGTGCTATAATGA
TAAAGAAAAGAGAGATATGCTTCCAACATATCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCAATTTTATTATTTAAA
AATAACCGTGCTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCAATCAAAGCA
ATGGTAAACATACCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References