Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 164002..164513 Replicon chromosome
Accession NZ_CP069319
Organism Kosakonia cowanii strain Pa82

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag JMT66_RS00785 Protein ID WP_054802690.1
Coordinates 164253..164513 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag JMT66_RS00780 Protein ID WP_232045137.1
Coordinates 164002..164256 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMT66_RS00760 (JMT66_00760) 160506..160952 - 447 WP_042718597.1 N-acetyltransferase -
JMT66_RS00765 (JMT66_00765) 160930..161511 - 582 WP_200580324.1 DNA-3-methyladenine glycosylase I -
JMT66_RS00770 (JMT66_00770) 161659..162339 + 681 WP_094418958.1 autotransporter domain-containing protein -
JMT66_RS00775 (JMT66_00775) 162581..163783 + 1203 WP_076769346.1 MFS transporter -
JMT66_RS00780 (JMT66_00780) 164002..164256 + 255 WP_232045137.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JMT66_RS00785 (JMT66_00785) 164253..164513 + 261 WP_054802690.1 Txe/YoeB family addiction module toxin Toxin
JMT66_RS00790 (JMT66_00790) 164617..165048 + 432 WP_042718589.1 organic hydroperoxide resistance protein -
JMT66_RS00795 (JMT66_00795) 165263..166945 + 1683 WP_200580325.1 kdo(2)-lipid A phosphoethanolamine 7''-transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-76)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10250.87 Da        Isoelectric Point: 9.7713

>T190138 WP_054802690.1 NZ_CP069319:164253-164513 [Kosakonia cowanii]
MTPRITPEAQADIDFWKQNDPKVKQKIDTLVRDALEHPFQGLGKPEALKHHKPLWSRRITKEHRLVYYIKDDSLIIVSCR
YHYVNL

Download         Length: 261 bp

>T190138 NZ_CP091121:4099298-4099642 [Serratia ureilytica]
ATGTGGCAAGTGGTGACCGTCGAACGATTCGACGACTGGTTTTTGGCGCTGAACAACGCCCAGCAAACAAGCATCCTGGC
GGCGATCTTCAAATTACAGACGTTCGGCCCGCAGTTGGCGCGGCCGCACGCCGATACGCTGCATTTTTCCGAAGCGGCCC
GGCAGTTGAAGGAGTTGCGCGTTCAACATCGCGGGCGCCCTTTCAGGGTGTTTTTCGCCTTTGACCCACAGCGGCAAGCA
GTATTGCTGTGCGGTGGCGATAAAACCAGCGACAAACGCTTTTACCAGCGCATGTTGCCCATCGCTGCCATGGAATTTTC
ACATTATCTGGCAACCCGGAGGTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9462.58 Da        Isoelectric Point: 4.5298

>AT190138 WP_232045137.1 NZ_CP069319:164002-164256 [Kosakonia cowanii]
MNMQHVNYTDARQNLASLMQQANDELAPILVTRKGAKSVVVIDAEEFASMQETLHLFSNPVNAAHIERSIQQAESGDLQE
YKFE

Download         Length: 255 bp

>AT190138 NZ_CP091121:4099648-4099950 [Serratia ureilytica]
ATGGCCAAACCGTTATCCCAACTGATCGACAAGCTCGATCCCGCCGTCGTTGCCGCAGCCAGGCAAAAGGCGGACAAGGA
AATTTTCGAACTGCGGCTGGCAATGCTGAGGGAAGAGCTGGCGGTCTCTCAGGTTGAATTGGCGAAGCGGCTCGGTATCA
GCCAACCCTCCGTCGCCAATTTGGAAAAGCGCGGCAGCGAAATAAAGCTGTCGTCGCTCAAACGCTATATCGAGGCGATG
GGCGGCACGCTGTCGCTGGATGTGCAATTGCCCAATGGCCAGCACCGCCGCATGACGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References