Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 875078..875895 Replicon chromosome
Accession NZ_CP069318
Organism Delftia lacustris strain R54

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag JQN63_RS03940 Protein ID WP_203400366.1
Coordinates 875078..875569 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag JQN63_RS03945 Protein ID WP_016448384.1
Coordinates 875566..875895 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JQN63_RS03910 870199..870683 + 485 Protein_766 cobalamin biosynthesis protein -
JQN63_RS03915 870680..871558 + 879 WP_154833464.1 precorrin-4 C(11)-methyltransferase -
JQN63_RS03920 871555..872352 + 798 WP_203400364.1 precorrin-6A synthase (deacetylating) -
JQN63_RS03925 872416..872745 + 330 WP_013800515.1 DHCW motif cupin fold protein -
JQN63_RS03930 873021..874436 + 1416 WP_203400365.1 chloride channel protein -
JQN63_RS03935 874551..875063 + 513 WP_016448386.1 MgtC/SapB family protein -
JQN63_RS03940 875078..875569 - 492 WP_203400366.1 type II toxin-antitoxin system YhaV family toxin Toxin
JQN63_RS03945 875566..875895 - 330 WP_016448384.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
JQN63_RS03950 875992..878235 - 2244 WP_203400367.1 TonB-dependent receptor -
JQN63_RS03955 878346..878741 - 396 WP_203400368.1 hypothetical protein -
JQN63_RS03960 878770..879432 - 663 WP_016452692.1 pyridoxamine 5'-phosphate oxidase family protein -
JQN63_RS03965 879503..880309 + 807 Protein_777 helix-turn-helix transcriptional regulator -
JQN63_RS03970 880402..880677 + 276 WP_016448378.1 type II toxin-antitoxin system ParD family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(16-152)

Antitoxin

PrlF antitoxin

(8-107)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 18775.30 Da        Isoelectric Point: 9.9304

>T190131 WP_203400366.1 NZ_CP069318:c875569-875078 [Delftia lacustris]
MSAVPPAPLRIHGWTVFMHPLFLAQLQALSHEVEGLKTKDPGGYTRKNATKRLAAIRKLAFDVIPQDPTRPDYRQGHTLG
EEHKHWFRARFFQQYRLFFRFHAPSKIIVFAWVNDEDTRRAYEGSDDAYRVFRKMLANGHPAGDWDSLLAQAESPPPDSQ
PHA

Download         Length: 492 bp

>T190131 NZ_CP091120:c4166243-4165821 [Serratia marcescens]
GTGGCCCAGTGGCGATGTGATATCCGCATTTCCTGGCGCACCCAGCTTTTTTCCCTGTTGACTCATGGCGTTCTGATCTT
GCTGATCCTGATTTCGCCCTGGCCGGAAGGTTATGGCCCGCTTTGGCTGGTGCTGCTGACGCTGGTGGTGTTTCAGTGCA
TTCGTAGCCAGAAGCGCATCGCCGCAGTGCAGGGCGAGCTGCGGCTGCTGGCGGACCGGCGTTTCAGCTGGCACGGCCGA
GAATGGCGGCTGGCGAAAAAGCCCTGGATGCCGGGCTACGGCCTGCTGCTGACGCTGCAGCCGATGGAAGGCAAAAAGCG
CCGCCGGCTGTGGCTGGCTTCCGACTGCATGAGCAAAGAGGAGTGGCGCCACCTGCGGCAGCTGTTGCTGTATCCGCCGG
CGGGTAACGGCGAGGAACCCTGA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12062.53 Da        Isoelectric Point: 4.1858

>AT190131 WP_016448384.1 NZ_CP069318:c875895-875566 [Delftia lacustris]
MFSTLEAESTLTDRYQTTIPEAVRRALHLSKRDRIHYTILPGGEVVLSRADSAEDADPVLGQFLGFLAQDMAAHPERLQT
MDARLAQQIQALTEGIEVDLDAPLLADDE

Download         Length: 330 bp

>AT190131 NZ_CP091120:c4166490-4166224 [Serratia marcescens]
ATGGATATTAACAACAAAGCACGTATTCACTGGGCTTGCCGTCGTGGCATGCGCGAGCTGGACATCTCCATCATGCCGTT
CTTCGAATACGAATACGACAGCCTGAATGACGCGGACAAGGCGCTGTTTATCCGCCTGCTGGAGTGTGACGATCCCGATC
TGTTCAACTGGCTGATGAATCATGGCGCGCCGCAGGACGGCGAGCTGCAGAGAATGGTGACCCTGATCCAAACGCGAAAT
AAAGACCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References