190062

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2724983..2725319 Replicon chromosome
Accession NZ_CP069185
Organism Enterococcus faecalis strain L11

Toxin (Protein)


Gene name txpA Uniprot ID A0A1J6YG70
Locus tag JO410_RS13185 Protein ID WP_002396786.1
Coordinates 2724983..2725126 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2725270..2725319 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JO410_RS13165 2720199..2720414 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
JO410_RS13170 2720553..2721545 + 993 WP_002378862.1 biotin--[acetyl-CoA-carboxylase] ligase -
JO410_RS13175 2721712..2722350 - 639 WP_002378863.1 lytic polysaccharide monooxygenase -
JO410_RS13180 2723035..2724651 + 1617 WP_002378864.1 phosphatase PAP2/LCP family protein -
JO410_RS13185 2724983..2725126 + 144 WP_002396786.1 putative holin-like toxin Toxin
- 2725270..2725319 + 50 - - Antitoxin
JO410_RS13190 2725321..2730012 - 4692 WP_002378865.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5203.19 Da        Isoelectric Point: 8.6626

>T190062 WP_002396786.1 NZ_CP069185:2724983-2725126 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Download         Length: 144 bp

>T190062 NZ_CP091067:4526720-4526902 [Pseudomonas sp. BC42]
GTGCAAAGCAGACAGTTGATCAAGGAGCTTGAAGCCGCGGGATGGGTGCTGGAGCGAGTCACTGGCAGCCATCATCTGTT
CCAGCATCCCTACAGGCCCCACACCGTTCCAGTGCCTCACCCGAAGAAGGATCTGCCCCGGGGAACGGTCAGGGCCATCA
GGAAACTGGCCGGGCTGCTTTAG

Antitoxin


Download         Length: 50 bp

>AT190062 NZ_CP069185:2725270-2725319 [Enterococcus faecalis]
AATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J6YG70

Antitoxin

Download structure file

References