Detailed information of TA system TA190054

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 353537..353732
• Replicon: chromosome
• Accession: NZ_CP069185
• Organism: Enterococcus faecalis strain L11

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: JO410_RS01815
• Protein ID: WP_015543884.1
• Coordinates: 353637..353732 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	353537..353602 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JO410_RS01800	349168..350910	+	1743	WP_002401739.1	PTS transporter subunit EIIC	-
JO410_RS01805	350901..352934	+	2034	WP_002355275.1	transcription antiterminator	-
JO410_RS01810	352945..353379	+	435	WP_002355276.1	PTS sugar transporter subunit IIA	-
-	353537..353602	+	66	-	-	Antitoxin
JO410_RS01815	353637..353732	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
JO410_RS01820	353978..355750	+	1773	WP_002391520.1	PTS mannitol transporter subunit IICBA	-
JO410_RS01825	355765..356202	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
JO410_RS01830	356217..357371	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
JO410_RS01835	357440..358555	-	1116	WP_002377910.1	FAD-binding oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (3-110)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T190054 WP_015543884.1 NZ_CP069185:c353732-353637 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T190054 NZ_CP091066:c2071590-2071228 [Staphylococcus aureus]
ATGATTAGACGAGGAGATGTTTATTTAGCAGATTTATCACCAGTACAGGGATCTGAACAAGGGGGAGTCAGACCTGTAGT
CATAATTCAAAATGATACTGGTAATAAATATAGTCCTACAGTTATTGTTGCGGCAATAACTGGTAGGATTAATAAAGCGA
AAATACCGACACATGTAGAGATTGAAAAGAAAAAGTATAAATTGGATAAAGACTCAGTTATATTATTAGAACAAATTCGT
ACACTTGATAAAAAACGATTGAAAGAAAAACTGACATACTTATCCGATGATAAAATGAAAGAAGTAGATAATGCACTAAT
GATTAGTTTAGGGCTGAATGCAGTAGCTCATCAGAAAAATTAG

Antitoxin

Nucleotide

• Length: 66 bp

>AT190054 NZ_CP069185:353537-353602 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTTT

Structures

Antitoxin