Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3693340..3693562 Replicon chromosome
Accession NZ_CP069133
Organism Escherichia coli BW25113 substr. CHXR2G20

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag JQK31_RS17910 Protein ID WP_000141634.1
Coordinates 3693340..3693447 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3693496..3693562 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JQK31_RS17885 3688593..3689345 - 753 Protein_3493 cellulose biosynthesis protein BcsQ -
JQK31_RS17890 3689357..3689545 - 189 WP_001063318.1 YhjR family protein -
JQK31_RS17895 3689818..3691389 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
JQK31_RS17900 3691386..3691577 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
JQK31_RS17905 3691574..3693253 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
JQK31_RS17910 3693340..3693447 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3693496..3693562 + 67 - - Antitoxin
JQK31_RS17915 3693923..3695194 + 1272 WP_001295225.1 transporter -
JQK31_RS17920 3695224..3696228 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
JQK31_RS17925 3696225..3697208 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
JQK31_RS17930 3697219..3698121 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T189980 WP_000141634.1 NZ_CP069133:c3693447-3693340 [Escherichia coli BW25113]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T189980 NZ_CP069133:c3693447-3693340 [Escherichia coli BW25113]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT189980 NZ_CP069133:3693496-3693562 [Escherichia coli BW25113]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References