Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3693336..3693558 Replicon chromosome
Accession NZ_CP069132
Organism Escherichia coli BW25113 substr. CHXR1G20

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag JQK35_RS17910 Protein ID WP_000141634.1
Coordinates 3693336..3693443 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3693492..3693558 (+)

Genomic Context

JQK35_RS17895JQK35_RS17900JQK35_RS17905--JQK35_RS17915JQK35_RS17885JQK35_RS17890JQK35_RS17910JQK35_RS17920JQK35_RS17925JQK35_RS17930
Location: 3689814..3691385 (1572 bp)
Type: Others
Protein ID: WP_001204931.1
Location: 3691382..3691573 (192 bp)
Type: Others
Protein ID: WP_000988308.1
Location: 3691570..3693249 (1680 bp)
Type: Others
Protein ID: WP_000191622.1
Location: 3693492..3693558 (67 bp)
Type: Antitoxin
Protein ID: -
Location: 3693919..3695190 (1272 bp)
Type: Others
Protein ID: WP_001295225.1
Location: 3688589..3689341 (753 bp)
Type: Others
Protein ID: Protein_3493
Location: 3689353..3689541 (189 bp)
Type: Others
Protein ID: WP_001063318.1
Location: 3693336..3693443 (108 bp)
Type: Toxin
Protein ID: WP_000141634.1
Location: 3695220..3696224 (1005 bp)
Type: Others
Protein ID: WP_000107012.1
Location: 3696221..3697204 (984 bp)
Type: Others
Protein ID: WP_001196486.1
Location: 3697215..3698117 (903 bp)
Type: Others
Protein ID: WP_000084677.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JQK35_RS178853688589..3689341-753Protein_3493cellulose biosynthesis protein BcsQ-
JQK35_RS178903689353..3689541-189WP_001063318.1YhjR family protein-
JQK35_RS178953689814..3691385+1572WP_001204931.1cellulose biosynthesis protein BcsE-
JQK35_RS179003691382..3691573+192WP_000988308.1cellulose biosynthesis protein BcsF-
JQK35_RS179053691570..3693249+1680WP_000191622.1cellulose biosynthesis protein BcsG-
JQK35_RS179103693336..3693443-108WP_000141634.1type I toxin-antitoxin system toxic polypeptide LdrDToxin
-3693492..3693558+67--Antitoxin
JQK35_RS179153693919..3695190+1272WP_001295225.1transporter-
JQK35_RS179203695220..3696224-1005WP_000107012.1dipeptide ABC transporter ATP-binding subunit DppF-
JQK35_RS179253696221..3697204-984WP_001196486.1dipeptide ABC transporter ATP-binding protein-
JQK35_RS179303697215..3698117-903WP_000084677.1dipeptide ABC transporter permease DppC-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T189937 WP_000141634.1 NZ_CP069132:c3693443-3693336 [Escherichia coli BW25113]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T189937 NZ_CP091029:c789392-789015 [Escherichia coli]
ATGAAAACATTACCCGATACACACGTACGGGAGGCATCGAGCTGCCCGTCTCCCGTCACCATCTGGCAGACTCTGCTCTC
CCGACTACTGGGCCAGCATTACGGCCTTACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGCGATGCGGTGAACTTTCTCGTTGAAAAATACGCCCTAGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGGCCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGCATCCGGAGGCGAAACAATGA

Antitoxin


Download         Length: 67 bp

>AT189937 NZ_CP069132:3693492-3693558 [Escherichia coli BW25113]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
PDB5LBJ

Antitoxin

Download structure file

References