Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 423084..423783 Replicon chromosome
Accession NZ_CP069080
Organism Pseudomonas putida strain LWPZF

Toxin (Protein)


Gene name mqsR Uniprot ID A0A550F6I7
Locus tag JNO42_RS01980 Protein ID WP_019750831.1
Coordinates 423084..423380 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A7D5VVT2
Locus tag JNO42_RS01985 Protein ID WP_029380550.1
Coordinates 423382..423783 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JNO42_RS01960 (JNO42_01955) 418720..420345 + 1626 WP_047604117.1 twin-arginine translocation signal domain-containing protein -
JNO42_RS01965 (JNO42_01960) 420467..420943 + 477 WP_003254241.1 sigma-70 family RNA polymerase sigma factor -
JNO42_RS01970 (JNO42_01965) 421112..421591 + 480 WP_019750829.1 hypothetical protein -
JNO42_RS01975 (JNO42_01970) 421664..422989 + 1326 WP_239607216.1 MFS transporter -
JNO42_RS01980 (JNO42_01975) 423084..423380 + 297 WP_019750831.1 type II toxin-antitoxin system MqsR family toxin Toxin
JNO42_RS01985 (JNO42_01980) 423382..423783 + 402 WP_029380550.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
JNO42_RS01995 (JNO42_01990) 425181..426863 - 1683 WP_275591285.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
JNO42_RS02000 (JNO42_01995) 427399..428148 + 750 WP_003254232.1 electron transfer flavoprotein subunit beta/FixA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11094.88 Da        Isoelectric Point: 9.8759

>T189885 WP_019750831.1 NZ_CP069080:423084-423380 [Pseudomonas putida]
MEKRTPHCPLHRLQVLLSQGKVRTTQAATLGARSLGLGPYDMLDVVRGLSPGDFHKSMTSYNDHRIWQDVYRAQTAVGRV
YLKLTVVDDLLILSFKEL

Download         Length: 297 bp

>T189885 NZ_CP091024:302464-302694 [Escherichia coli]
CTGGATCAGCTATTTAAATCACCTTTACCTCAAGGAATCAAATGGACTGATATAGAATCTCTGGTTAAAGCGTTAGGCGG
AGAAATTAAGGAAGGTAGGGGGTCGCGCTGTAAGTTCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGT
CGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTGCGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14692.91 Da        Isoelectric Point: 4.9749

>AT189885 WP_029380550.1 NZ_CP069080:423382-423783 [Pseudomonas putida]
MKCPLCGGAELVAQSRDMPYRYKGEATVIPDIFGDYCPTCGEAVLGMDEAQRMSDLMTAFERKVNAAVVDPGFIAAMRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp

>AT189885 NZ_CP091024:302691-303050 [Escherichia coli]
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCTGCTGTTATCACTTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAAGGGG
AACTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A550F6I7

Antitoxin

Source ID Structure
AlphaFold DB A0A7D5VVT2

References