Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 65664..66505 Replicon plasmid P1
Accession NZ_CP069005
Organism Sulfitobacter mediterraneus strain SC1-11

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag JNX03_RS18950 Protein ID WP_203212333.1
Coordinates 65987..66505 (+) Length 173 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag JNX03_RS18945 Protein ID WP_203212332.1
Coordinates 65664..65990 (+) Length 109 a.a.

Genomic Context

JNX03_RS18925JNX03_RS18930JNX03_RS18935JNX03_RS18940JNX03_RS18945JNX03_RS18950JNX03_RS18955JNX03_RS18960JNX03_RS18965
Location: 61584..61973 (390 bp)
Type: Others
Protein ID: WP_203212328.1
Location: 62129..64111 (1983 bp)
Type: Others
Protein ID: WP_203212329.1
Location: 64188..64781 (594 bp)
Type: Others
Protein ID: WP_203212330.1
Location: 64884..65537 (654 bp)
Type: Others
Protein ID: WP_203212331.1
Location: 65664..65990 (327 bp)
Type: Antitoxin
Protein ID: WP_203212332.1
Location: 65987..66505 (519 bp)
Type: Toxin
Protein ID: WP_203212333.1
Location: 66599..66763 (165 bp)
Type: Others
Protein ID: WP_170850626.1
Location: 66753..66905 (153 bp)
Type: Others
Protein ID: WP_009820264.1
Location: 67008..71270 (4263 bp)
Type: Others
Protein ID: WP_203212334.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JNX03_RS1892561584..61973+390WP_203212328.1DUF3768 domain-containing protein-
JNX03_RS1893062129..64111+1983WP_203212329.1ParB/RepB/Spo0J family partition protein-
JNX03_RS1893564188..64781+594WP_203212330.1regulator-
JNX03_RS1894064884..65537+654WP_203212331.1hypothetical protein-
JNX03_RS1894565664..65990+327WP_203212332.1type II toxin-antitoxin system PrlF family antitoxinAntitoxin
JNX03_RS1895065987..66505+519WP_203212333.1type II toxin-antitoxin system YhaV family toxinToxin
JNX03_RS1895566599..66763+165WP_170850626.1hypothetical protein-
JNX03_RS1896066753..66905+153WP_009820264.1hypothetical protein-
JNX03_RS1896567008..71270+4263WP_203212334.1strawberry notch family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..152756152756


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(19-155)

Antitoxin

PrlF antitoxin

(9-104)


Sequences

Toxin        


Download         Length: 173 a.a.        Molecular weight: 19361.00 Da        Isoelectric Point: 9.7477

>T188834 WP_203212333.1 NZ_CP069005:65987-66505 [Sulfitobacter mediterraneus]
MSGDSVPAQAPLVVNGWSIYAHPLFLDQLEGLILEVEARKARDPKTWRKKNPTKRLAAIFKLVTEAIPADPGAAAYRQGS
TLGDHRKHWFRAKFFQQYRLFYRFNSDAKVIVVAWVNDDKTLRAYGSKTDAYATFKGMLEDGNPPDNFDALLKEAAAADK
RFETSLEAAPDR

Download         Length: 519 bp

>T188834 NZ_CP090575:1923480-1923668 [Staphylococcus epidermidis]
ATGAGCTTACATTTCCAAATTTTGCTGTGGCTTTCTATCTTATTTATCATCGCAGGAACGATATTATTGGTAACAATGCT
TAAAACTAAAAAAGAAGAACGAAAAGAATCTTATCTAGGCTTTACTGTAATTTTCTTAATCTTTGGTTTTGCCATCTTAA
TTTATACTTTTATATTCGGAATTTTATAA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 11838.30 Da        Isoelectric Point: 4.3818

>AT188834 WP_203212332.1 NZ_CP069005:65664-65990 [Sulfitobacter mediterraneus]
MTALAQDVSKLTDRYQTTVPAGVRKQLKLGKGDQIRYCTEPSGRVYIEPVRSDEEDPVLGAFLDFVEADIKAHPDRIRAF
DGALHGRLAALVGDVDVDLDGPLSLEDE

Download         Length: 327 bp

>AT188834 NZ_CP090575:1923198-1923455 [Staphylococcus epidermidis]
ATGAAATTAAACAAAGCAAATATATTCAATTTGATATTCACCATTTTATTTTTTTCATTTAACATTCTCATAACCTATAA
CGCAAATATAGATTATAAGTTATGGTTAATACCTGGTTTAGCAATTTGTGGTTTTGCTCTTTTTTCAAGCTTGACCTTAG
TAATTATCTATAGTGATTTATTCAGTGAAATATTATTTTTTATCAACATTATCTTAGCACTGTATTACATTTATCCGATT
TTTTATGAATTTGTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References