Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1055563..1055842 Replicon chromosome
Accession NZ_CP068682
Organism Staphylococcus aureus strain NCCP11854

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag JKV48_RS05135 Protein ID WP_001802298.1
Coordinates 1055563..1055667 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1055663..1055842 (-)

Genomic Context


JKV48_RS05105JKV48_RS05110JKV48_RS05125JKV48_RS05130JKV48_RS05135JKV48_RS05160JKV48_RS05115JKV48_RS05120--JKV48_RS05145JKV48_RS05150JKV48_RS05155
Location: 1050957..1051739 (783 bp)
Type: Others
Protein ID: WP_235103128.1
Location: 1051807..1052664 (858 bp)
Type: Others
Protein ID: WP_000370919.1
Location: 1053740..1054876 (1137 bp)
Type: Others
Protein ID: Protein_1012
Location: 1054919..1055402 (484 bp)
Type: Others
Protein ID: Protein_1013
Location: 1055563..1055667 (105 bp)
Type: Toxin
Protein ID: WP_001802298.1
Location: 1058924..1059589 (666 bp)
Type: Others
Protein ID: WP_001024088.1
Location: 1052858..1053072 (215 bp)
Type: Others
Protein ID: Protein_1010
Location: 1053359..1053451 (93 bp)
Type: Others
Protein ID: WP_031844941.1
Location: 1055663..1055842 (180 bp)
Type: Antitoxin
Protein ID: -
Location: 1056116..1057207 (1092 bp)
Type: Others
Protein ID: WP_000495695.1
Location: 1057473..1058450 (978 bp)
Type: Others
Protein ID: WP_000019732.1
Location: 1058452..1058772 (321 bp)
Type: Others
Protein ID: WP_000139802.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JKV48_RS05105 (JKV48_05080)1050957..1051739+783WP_235103128.1ABC transporter ATP-binding protein-
JKV48_RS05110 (JKV48_05085)1051807..1052664+858WP_000370919.1HAD family hydrolase-
JKV48_RS051151052858..1053072-215Protein_1010exotoxin-
JKV48_RS05120 (JKV48_05090)1053359..1053451-93WP_031844941.1hypothetical protein-
JKV48_RS05125 (JKV48_05095)1053740..1054876+1137Protein_1012SAP domain-containing protein-
JKV48_RS05130 (JKV48_05100)1054919..1055402+484Protein_1013recombinase family protein-
JKV48_RS05135 (JKV48_05105)1055563..1055667+105WP_001802298.1hypothetical proteinToxin
-1055663..1055842-180--Antitoxin
JKV48_RS05145 (JKV48_05110)1056116..1057207-1092WP_000495695.1hypothetical protein-
JKV48_RS05150 (JKV48_05115)1057473..1058450-978WP_000019732.1CDF family zinc efflux transporter CzrB-
JKV48_RS05155 (JKV48_05120)1058452..1058772-321WP_000139802.1Zn(II)-responsive metalloregulatory transcriptional repressor CzrA-
JKV48_RS05160 (JKV48_05125)1058924..1059589+666WP_001024088.1SDR family oxidoreductase-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T187521 WP_001802298.1 NZ_CP068682:1055563-1055667 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T187521 NZ_CP089880:3872010-3872228 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATTCCGACCTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 180 bp

>AT187521 NZ_CP068682:c1055842-1055663 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A2I7Y9L9


Antitoxin

Download structure file

References