Detailed information of TA system TA187327

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 983259..983518
• Replicon: chromosome
• Accession: NZ_CP068576
• Organism: Staphylococcus equorum strain KS1030

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: JL104_RS04620
• Protein ID: WP_002511402.1
• Coordinates: 983259..983366 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	983356..983518 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JL104_RS04590	978501..979373	+	873	WP_202809235.1	ABC transporter ATP-binding protein	-
JL104_RS04595	979373..980101	+	729	WP_002507157.1	ABC transporter permease subunit	-
JL104_RS04600	980184..980744	-	561	WP_002507158.1	thioredoxin family protein	-
JL104_RS04605	980915..981400	+	486	WP_069819006.1	hypothetical protein	-
JL104_RS04610	981494..982054	+	561	WP_002511403.1	DUF1700 domain-containing protein	-
JL104_RS04615	982051..982902	+	852	WP_002507161.1	DUF4097 family beta strand repeat protein	-
JL104_RS04620	983259..983366	+	108	WP_002511402.1	putative holin-like toxin	Toxin
-	983356..983518	-	163	-	-	Antitoxin
JL104_RS04625	983824..984567	+	744	WP_069827917.1	HAD-IIB family hydrolase	-
JL104_RS04630	984587..984742	+	156	WP_002507163.1	hypothetical protein	-
JL104_RS04635	984852..985145	+	294	WP_040762580.1	hypothetical protein	-
JL104_RS04640	985123..985773	+	651	WP_002507165.1	cytochrome P450	-
JL104_RS04645	986356..987396	-	1041	WP_002507167.1	choloylglycine hydrolase	-
JL104_RS04650	987891..988061	+	171	WP_002507168.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (4-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3756.72 Da
• Isoelectric Point: 10.4997

>T187327 WP_002511402.1 NZ_CP068576:983259-983366 [Staphylococcus equorum]
VVPIVEALHLMLGFGTFIVTLLGLVVAIVKLSHKK

Nucleotide

• Length: 108 bp

>T187327 NZ_CP089781:c3056542-3056126 [Mycobacterium tuberculosis]
ATGACCACGCGCTATTTGCTCGACAAATCAGCGGCTTACCGCGCGCACTTGCCCGCGGTCCGACATCGCTTGGAACCGTT
GATGGAACGCGGTCTACTGGCCCGGTGCGGCATTACCGATCTCGAGTTCGGAGTCTCGGCGCGTTCCCGCGAGGACCATC
GAACACTGGGCACCTACCGGCGTGACGCGCTCGAATACGTCAACACCCCCGACACCGTGTGGGTTCGTGCATGGGAGATC
CAAGAAGCATTGACCGACAAGGGATTTCACCGCTCGGTCAAGATCCCGGACTTGATCATTGCGGCGGTCGCCGAGCATCA
CGGCATACCCGTCATGCACTACGACCAAGACTTCGAACGCATCGCCGCCATCACACGGCAACCCGTGGAATGGGTGGTGG
CCCCAGGGACAGCGTGA

Antitoxin

Nucleotide

• Length: 163 bp

>AT187327 NZ_CP068576:c983518-983356 [Staphylococcus equorum]
ATTTGATAATATTTTTATGTTGTGGTAATTTATATATAGAAAAAGGGCAACACACCATAAGTGTATCGCCCTAATGAGCC
CGTTAAAAAGACGGTGGCTGGAATTTAATAATGATTAAATAATCATCTCATCCTCGCCAAAGTTAGAGATGGTTATTTTT
TAT

Structures

Antitoxin