Detailed information of TA system TA186962

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 332413..332607
• Replicon: chromosome
• Accession: NZ_CP068249
• Organism: Enterococcus faecalis strain T90-1

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: JG557_RS01675
• Protein ID: WP_015543884.1
• Coordinates: 332512..332607 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	332413..332477 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JG557_RS01660	328031..329773	+	1743	WP_002385355.1	PTS transporter subunit EIIC	-
JG557_RS01665	329764..331797	+	2034	WP_002361171.1	transcription antiterminator	-
JG557_RS01670	331808..332242	+	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
-	332413..332477	+	65	-	-	Antitoxin
JG557_RS01675	332512..332607	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
JG557_RS01680	332853..334625	+	1773	WP_002387897.1	PTS mannitol transporter subunit IICBA	-
JG557_RS01685	334640..335077	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
JG557_RS01690	335092..336246	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
JG557_RS01695	336313..337428	-	1116	WP_002380024.1	FAD-binding oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T186962 WP_015543884.1 NZ_CP068249:c332607-332512 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T186962 NZ_CP089775:c2227749-2227330 [Mycobacterium tuberculosis]
ATGATCGTGGACACAAGCGCCGTGGTGGCCCTGGTTCAAGGCGAGCGGCCGCACGCCACCCTGGTCGCGGCCGCCCTGGC
CGGCGCCCATAGCCCCGTCATGTCTGCACCCACCGTCGCCGAATGCCTGATTGTCTTGACCGCCCGTCACGGCCCCGTTG
CGCGCACGATCTTCGAACGACTTCGCAGCGAAATCGGCTTGAGCGTGTCATCTTTCACCGCCGAGCATGCCGCTGCCACG
CAACGAGCCTTTCTGCGATACGGCAAGGGGCGCCACCGCGCGGCTCTCAACTTCGGAGACTGTATGACGTACGCGACCGC
CCAGCTGGGCCACCAACCACTGCTGGCCGTCGGCAACGACTTCCCGCAAACCGACCATGAGTTCCGCGGCGTCGTCGGCT
ACTGGCCAGGCGTCGCGTAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT186962 NZ_CP068249:332413-332477 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Structures

Antitoxin