Detailed information of TA system TA186881

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 249887..250048
• Replicon: chromosome
• Accession: NZ_CP068219
• Organism: Staphylococcus pasteuri strain FDAARGOS_1151

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: I6J08_RS01385
• Protein ID: WP_108017145.1
• Coordinates: 249887..249982 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	250014..250048 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6J08_RS01375 (I6J08_01375)	245822..248755	+	2934	WP_017638039.1	AAA family ATPase	-
I6J08_RS01380 (I6J08_01380)	248755..249696	+	942	WP_017638040.1	3'-5' exoribonuclease YhaM	-
I6J08_RS01385 (I6J08_01385)	249887..249982	+	96	WP_108017145.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	250014..250048	-	35	-	-	Antitoxin
I6J08_RS01390 (I6J08_01390)	250142..251134	-	993	WP_017638041.1	peptidylprolyl isomerase	-
I6J08_RS01395 (I6J08_01395)	251317..251874	-	558	WP_029056283.1	DUF3267 domain-containing protein	-
I6J08_RS01400 (I6J08_01400)	252070..252441	-	372	WP_017638293.1	YtxH domain-containing protein	-
I6J08_RS01405 (I6J08_01405)	252519..252944	-	426	WP_017638294.1	HIT family protein	-
I6J08_RS01410 (I6J08_01410)	253076..253816	+	741	WP_017638295.1	ABC transporter ATP-binding protein	-
I6J08_RS01415 (I6J08_01415)	253809..255032	+	1224	WP_017638296.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3674.38 Da
• Isoelectric Point: 8.0878

>T186881 WP_108017145.1 NZ_CP068219:249887-249982 [Staphylococcus pasteuri]
MSEIFVHIMTTVISGCMVTLFAHWLRHRNDK

Nucleotide

• Length: 96 bp

>T186881 NZ_CP089774:721594-721989 [Mycobacterium tuberculosis]
ATGGTGATCGACACGTCCGCGCTCGTTGCGATGCTCAGCGACGAGCCAGACGCAGAGCGGTTCGAGGCCGCCGTCGAAGC
CGACCACATCCGGCTGATGTCGACGGCGTCTTACCTGGAAACGGCACTCGTGATAGAAGCCCGCTTCGGTGAACCGGGCG
GACGTGAGCTGGATCTGTGGCTTCATCGCGCCGCGGTCGACCTTGTTGCCGTGCATGCCGACCAAGCGGATGCCGCGCGC
GCCGCCTACCGCACGTACGGCAAGGGAAGGCATCGTGCGGGGCTCAACTACGGCGACTGCTTCTCATACGGCCTCGCCAA
GATCAGCGGCCAGCCACTCCTGTTCAAGGGCGAAGATTTCCAACACACCGACATCGCCACGGTCGCGCTGCCCTAA

Antitoxin

Nucleotide

• Length: 35 bp

>AT186881 NZ_CP068219:c250048-250014 [Staphylococcus pasteuri]
ACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin